Results 51 to 60 of about 243,110 (311)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Functional analysis of four bile salt hydrolase and penicillin acylase family members in Lactobacillus plantarum WCFS1 [PDF]

, 2008
Bile salts play an important role in the digestion of lipids in vertebrates and are synthesized and conjugated to either glycine or taurine in the liver.
Lambert, J.M., Vos, W.M., de, Kleerebezem, M., Bongers, R.S.   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Lactobacillus plantarum ftsH gene is a novel member of the CtsR stress response regulon [PDF]

, 2008
FtsH proteins have dual chaperone-protease activities and are involved in protein quality control under stress conditions. Although the functional role of FtsH proteins has been clearly established, the regulatory mechanisms controlling ftsH expression ...
D. Fiocco, Kleerebezem, M., FIOCCO D., Muscariello, Lidia, Collins, M., Hols, Pascal, Muscariello, L., SPANO G., Kleerebezem, Michiel, M., T. Msadek, Kleerebezem, Michiel, Fiocco, Daniela, Hols, Pascal, P., HOLS P., Spano, G., M. Collins, Hols, P., G. Spano, P. Hols, KLEEREBEZEM M., L. Muscariello, Msadek, Tarek, MSADEK T., Spano, Giuseppe, M. Kleerebezem, Collins, Michael, Fiocco, D., COLLINS M., Msadek, T.   +28 more
core   +1 more source

Lactobacillus Species as Probiotics: Isolation Sources and Health Benefits [PDF]

, 2022
Recently, the attention to exploring and applying probiotics has been increased. Probiotics are living microscopic organisms that have valuable impacts on health when consumed in adequate amounts.
Ashraf Y. Khalifa, Ameera M. Al-Yami, Abeer T. Al-Mousa, Sarah A. Al-Otaibi   +3 more
core   +1 more source

Phase Engineering of Nanomaterials (PEN): Evolution, Current Challenges, and Future Opportunities

Advanced Materials, EarlyView.
This review summarizes the synthesis, phase transition, advanced characterization spanning ex situ to in situ and operando techniques, and diverse applications of phase engineering of nanomaterials (PEN). It further outlines key challenges and future opportunities, such as phase stability, architecture control, and artificial intelligence (AI)‐driven ...
Ye Chen, Zhanxi Fan, Jingjie Ge, Qiyuan He, Zhuangchai Lai, Jiawei Liu, Chaoliang Tan, Hua Zhang   +7 more
wiley   +1 more source

Region‐Specific Profiling of the Gut Microbiome and Metabolite Landscape in Response to Dietary Intervention Using Electronics‐Free Ingestible Smart Sampling Capsules

Advanced Materials Technologies, EarlyView.
Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik, Caitlyn Sullivan, Akshay Krishnakumar, Fangxin Chen, Anna Clapp Organski, Wayne W. Campbell, Jay S. Johnson, Tzu‐Wen L. Cross, Rahim Rahimi   +8 more
wiley   +1 more source

Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization [PDF]

, 2010
Contains fulltext : 88219.pdf (Publisher’s version ) (Open Access)BACKGROUND: Probiotics can be used to stimulate or regulate epithelial and immune cells of the intestinal mucosa and generate beneficial mucosal immunomodulatory effects.
Kleerebezem, M., Vos, P., de, Bilsen, J., van Bilsen Jolanda, Meijerink Marjolein, Savelkoul, H.F.J., Bron, P.A., Savelkoul Huub F., Bilsen, J.G.P.M., van, Huub F. Savelkoul, Wells Jerry M., Vos, P., Marjolein Meijerink, Jolanda van Bilsen, Bron, Peter A., Wells, J., Savelkoul, Huub F., de Vos Paul, Huub F Savelkoul, Saskia van Hemert, Michiel Wels, van Hemert Saskia, Meijerink, M., Jerry M Wells, Kleerebeezem, M., van Bilsen, Jolanda, Wels, Michiel, Kleerebezem, Michiel, Paul de Vos, Michiel Kleerebezem, Kleerebezem Michiel, Peter A. Bron, Taverne, Nico, Taverne Nico, Taverne, N., van Hemert, Saskia, de Vos, Paul, Bron Peter A., Peter A Bron, de Vos, Paul; id_orcid, Wells, J.M., Wels Michiel, Nico Taverne, Hemert, S. van, Hemert, S., van, Wells, Jerry M., Jerry M. Wells, Wels, M.W.W., Sanders, M.W.W., Meijerink, Marjolein   +49 more
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Modeling in the interactions of Lactobacillus curvatus colonies in solid medium : consequences for food quality an safety [PDF]

, 2002
The growth process of Lactobacillus curvatus colonies was quantified by a coupled growth and diffusion equation incorporating a volumetric rate of lactic acid production. Analytical solutions were compared to numerical ones, and both were able to predict
Martens, D.E., K. van 't Riet, W. van Breukelen, P. K. Malakar, Zwietering, M.H., D. E. Martens, Riet, K., van 't, Breukelen, W., van, Malakar, P.K., Boom, R.M., R. M. Boom, M. H. Zwietering   +11 more
core   +1 more source