Results 71 to 80 of about 94,892 (196)

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, November 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Carbohydrate active enzymes in Lactobacillus crispatus – a possible link between the pullulanase gene and growth on glycogen

, 2018
Update on Lactobacillus crispatus type 1 pullulanase experimental ...
Rosanne Hertzberger (4111210)
core   +1 more source

HIV Inhibition by Lactobacilli: Easier in a Test Tube Than in Real Life

mBio, 2015
A lactobacillus-dominant vaginal microbiota has been shown to decrease heterosexual HIV transmission. Nunn et al. now report that a vaginal microbiota dominated by Lactobacillus crispatus is associated with a relative inability of HIV pseudoviral ...
Steven S. Witkin, Iara M. Linhares
doaj   +1 more source

Exploring Cervical Cancer‐Associated Vaginal and Cervical Microbiota via 16S rRNA Sequencing

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This 16S sequencing study identified a dysbiotic cervical microbiota (increased diversity, reduced Lactobacillus, enriched Prevotella) specifically linked to high‐risk HPV infection. These microbial alterations, shaped by the HPV‐driven microenvironment, offer novel targets for biomarkers and mechanistic research in cervical carcinogenesis.
Guojiao Wang, Xiaotong Liu, Zimo Wang, Huadong Tian, Yan Li, Yuexi Luo   +5 more
wiley   +1 more source

Lactobacillus crispatus dominant vaginal microbiome is associated with inhibitory activity of female genital tract secretions against Escherichia coli.

PLoS ONE, 2014
ObjectiveFemale genital tract secretions inhibit E. coli ex vivo and the activity may prevent colonization and provide a biomarker of a healthy microbiome. We hypothesized that high E.
Jeny P Ghartey, Benjamin C Smith, Zigui Chen, Niall Buckley, Yungtai Lo, Adam J Ratner, Betsy C Herold, Robert D Burk   +7 more
doaj   +1 more source

Diverse Expression of Antimicrobial Activities Against Bacterial Vaginosis and Urinary Tract Infection Pathogens by Cervicovaginal Microbiota Strains of Lactobacillus gasseri and Lactobacillus crispatus

Frontiers in Microbiology, 2019
We aimed to analyze the strain-by-strain expression of a large panel of antimicrobial activities counteracting the virulence mechanisms of bacterial vaginosis-associated Prevotella bivia CI-1 and Gardnerella vaginalis 594, pyelonephritis-associated ...
Fabrice Atassi, Fabrice Atassi, Diane L. Pho Viet Ahn, Diane L. Pho Viet Ahn, Diane L. Pho Viet Ahn, Vanessa Lievin-Le Moal, Vanessa Lievin-Le Moal, Vanessa Lievin-Le Moal   +7 more
doaj   +1 more source

What is in the Dust? Species‐Level Profiling Reveals Pathogenic and Protective Potential of Microbial Communities in Daycare and Home Environments

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Daycare and home dust predominantly harbour commensal and environmental bacteria; however, a significant proportion remains unclassified, indicating routine childhood exposure to novel microorganisms. Both environments contain species with probiotic and immunostimulatory properties that may confer protection against non‐communicable diseases including ...
Jill A. McKay, Richard Harding‐Crooks, Vartul Sangal   +2 more
wiley   +1 more source

Longitudinal analysis of the vaginal microflora in pregnancy suggests that L. crispatus promotes the stability of the normal vaginal microflora and that L. gasseri and/or L. iners are more conducive to the occurrence of abnormal vaginal microflora

BMC Microbiology, 2009
Background Despite their antimicrobial potential, vaginal lactobacilli often fail to retain dominance, resulting in overgrowth of the vagina by other bacteria, as observed with bacterial vaginosis.
Temmerman Marleen, De Backer Ellen, Claeys Geert, Verhelst Rita, Verstraelen Hans, Vaneechoutte Mario   +5 more
doaj   +1 more source

Probiogenomics Analysis of 97 Lactobacillus crispatus Strains as a Tool for the Identification of Promising Next-Generation Probiotics

Microorganisms, 2020
Members of the genus Lactobacillus represent the most common colonizers of the human vagina and are well-known for preserving vaginal health and contrasting the colonization of opportunistic pathogens.
Federico Fontana, Giulia Alessandri, Gabriele Andrea Lugli, Leonardo Mancabelli, Giulia Longhi, Rosaria Anzalone, Alice Viappiani, Marco Ventura, Francesca Turroni, Christian Milani   +9 more
doaj   +1 more source