Results 151 to 160 of about 239,392 (300)

Lactose intolerance and probiotics: from pathophysiological mechanisms to clinical applications. [PDF]

Antonie Van Leeuwenhoek
Perets TT, Gingold-Belfer R, Dickman R.
europepmc   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Clinical outcomes of two lactose-free formulas in the management of acute childhood diarrhea. [PDF]

World J Clin Pediatr
Phavichitr N, Tantibhaedhyangkul R, Dumrisilp T, Prachuapthunyachart S, Chanpreecha W, Ratanamongkol P, Chongsrisawat V.   +6 more
europepmc   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Preterm Birth International Collaborative Australasia Branch: Expert Consensus on Diagnosis and Treatment of Neonatal Lactose Intolerance (2025). [PDF]

Pediatr Discov
Wang Z, Han S, Lin X, Wu H, Xu L, Tang J, Hao W, Yu C, Tong X, Zhang J, Ju R, Xie X, Chen L, Li F, Zhu X, Xu L, Geng L, Zhou W, Ren X, Li C, Chen G, Tang W, Duan J, Zhao Z, Pan T, Li Z, Wu Y, Zhuang S, Ouyang Y, Xu F, Chen Z, Liu Y, Peng Z, Bao L, He Y, Kong L, Zheng X, Xu L, Shen Q, Zhang Q, Li J, Wang J, Shi Y.   +42 more
europepmc   +1 more source

A new branch of mammalian vitamin B6 metabolism: AKR1C‐mediated conversion of pyridoxal to pyridoxine and 4‐pyridoxolactone

The FEBS Journal, EarlyView.
Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito, Yasuyuki Kitaura, Kyoka Iino, Kazuya Toriumi, Hyunah Noh, Naoya Ogawa, Makoto Arai, Hisashi Hemmi, Tomokazu Ito   +8 more
wiley   +1 more source

Engineering of <i>Escherichia coli</i> for D-tagatose production from lactose and whey permeate via the tagatose-6-phosphate pathway. [PDF]

Curr Res Food Sci
Abzach A, Ben-Adiva R, Gruzdev N, Musa S, Yadid I.   +4 more
europepmc   +1 more source

Growth, Feeding and Nutrition in Rett Syndrome: Retrospective Audit of Twenty Years' Experience From an Australian Multidisciplinary Management Clinic

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim This study reviewed the nutritional status, feeding skills, safety, and management of patients with Rett syndrome during childhood and adolescence. Method Retrospective chart review of 103 females with classical Rett syndrome, aged ≤ 18 years, attending a Rett syndrome Multidisciplinary Management clinic in a tertiary hospital from 2000 to
Susan Thompson, Toni Bird, Gloria Tzannes, Carolyn Ellaway   +3 more
wiley   +1 more source

Metabolic pathway analysis reveals hierarchical pentose sugar utilization and metabolic flexibility of <i>Bifidobacterium longum</i>. [PDF]

Gut Microbes
Friess L, McAuliffe FM, Cotter PD, Shiver AL, Huang KC, de Jong A, van Sinderen D.   +6 more
europepmc   +1 more source

Between Financial and Socioemotional Wealth: Navigating Knotted Tensions in Family Business Innovation

Journal of Product Innovation Management, EarlyView.
ABSTRACT Current research on family business innovation tends to isolate individual tensions for analysis, while in reality, these tensions often arise in complex entanglements. To fill this research void, we focus on understanding how multiple tensions occur in the innovation process, how these tensions are entangled, and how they are managed. We turn
Elias Hadjielias, Michael Christofi, Carlotta Benedetti   +2 more
wiley   +1 more source