Results 51 to 60 of about 96,045 (313)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

PSYNDEX Tests Review für H-LAD - Heidelberger Lautdifferenzierungstest

, 2016
This is a PSYNDEX Tests Review of H-LAD - Heidelberger Lautdifferenzierungstest. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Karadere, Gülay
core   +1 more source

IBN ‘ARABĪ’S CREATIVE IMAGINATION AND ITS ECHOES IN D.H. LAWRENCE’S WOMEN IN LOVE

Kanz Philosophia: A Journal for Islamic Philosophy and Mysticism
This paper employs textual analysis and comparative literary methods to examine the mystical and spiritual dimensions of D. H. Lawrence's Women in Love through the lens of sufi mysticism.
Cyrine Kortas
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

LAD atlas

, 2019
Coordinates for LAD atlas in tabular txt ...
Daan Peric Hupkes, carolyn de graaf, Ludo Pagie, jop kind, Bas van Steensel   +4 more
core   +1 more source

Fistula between the left anterior descending artery and the pulmonary trunk

European Journal of Case Reports in Internal Medicine
Background: Coronary artery fistulas are usually asymptomatic anomalies diagnosed most often incidentally during conventional coronary angiography or computed tomography angiography (CTA) of the coronary arteries. Case report: We present the case of a 74-
Paweł Święch, Przemysław Jaźwiec, Paweł Błaszkiewicz, Andrzej Bazan   +3 more
doaj   +1 more source

Effect of Thermal Treatment of Fast Growing Wood Fibers on Physical and Mechanical Properties of Light Medium Density Fiberboard

High Temperature Materials and Processes, 2011
This study investigated physical and mechanical properties of the light medium density fiberboard (MDF) panels made from thermally treated wood fibers of eucalyptus camaldulensis at three different temperatures (393 K, 423 K or 453 K) for 30 or 60 min in
Jarusombuti Songklod, Ayrilmis Nadir, Fueangvivat Vallayuth, Bauchongkol Piyawade   +3 more
doaj   +1 more source

Long non‐coding RNA XIST expedites lung adenocarcinoma progression through upregulating MDM2 expression via binding to miR‐363‐3p

Thoracic Cancer, 2020
Background Lung adenocarcinoma (LAD) is a highly aggressive malignant tumor which threatens the health and life of the population. Long non‐coding RNA X‐inactive specific transcript (XIST) and mouse double minute clone 2 (MDM2) are connected with the ...
Hao Rong, Bing Chen, Xing Wei, Jun Peng, Ke Ma, Song Duan, Jintao He   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Detection of severe left anterior descending coronary artery stenosis by transthoracic evaluation of resting coronary flow velocity dynamics

Heart International, 2010
In the presence of severe stenosis, coronary artery flow may be reduced at rest. Recent advances in echocardiography have made non-invasive sampling of velocities in the left an­terior descending coronary artery (LAD) possible.
Edward G. Abinader, Camilia Shahla, Dawod Saleh Sharif, Amal Sharif-Rasslan   +3 more
doaj   +1 more source