Results 71 to 80 of about 96,045 (313)

LAD Asymptotics under Conditional Heteroskedasticity with Possibly Infinite Error Densities [PDF]

open access: yes
Least absolute deviations (LAD) estimation of linear time-series models is considered under conditional heteroskedasticity and serial correlation. The limit theory of the LAD estimator is obtained without assuming the finite density condition for the ...
Jin Seo Cho   +2 more
core  

Pre-Intervention Assessment of Toxocara Infection in Dogs in Vietnam: A Community-Based Cross-Sectional Study

open access: yesAnimals
Dogs are key reservoirs of zoonotic infections, including Toxocara canis, a widely distributed parasite of major public health concern. In Vietnam, the parasite is highly prevalent in dog populations and humans.
Minh-Trang Thi Hoang   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Our boys.

open access: yes, 1907
Editor: 1907-1910, Judson Titsworth; 1911-1948, W.J.C. Ralph; 1949-Jan. 1951, Peter E. Cupery.Published at: Wauwatosa, Wis., 1912-May 1927; Hartland, Wis., Oct. 1927-Jan. 1949; Dousman, Wis., Apr.
Lad Lake, Inc.
core  

Left Axis Deviation in Electrocardiogram with Normal QRS Duration in Ambulatory Adults without Cardiac Symptoms: A Possible Marker of Glucose Intolerance

open access: yesJournal of Nepal Medical Association, 2013
Introduction: We are increasingly noticing isolated left axis deviation (LAD) in electrocardiogram in younger people with diabetes without obvious heart disease and association of LAD with glucose intolerance has not been explicitly raised before.
Amar Paudyal   +5 more
doaj   +3 more sources

Notch-1 Confers Chemoresistance in Lung Adenocarcinoma to Taxanes through AP-1/microRNA-451 Mediated Regulation of MDR-1

open access: yesMolecular Therapy: Nucleic Acids, 2016
We previously demonstrated that expression of Notch-1 is associated with poor prognosis in lung adenocarcinoma (LAD) patients. The aim of this study is to reveal whether Notch-1 was associated with Taxanes-resistant LAD and, the underlying mechanisms. We
Jiayuan Huang   +10 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Dual LAD system – A case report and lessons learnt from past nomenclature system

open access: yesIHJ Cardiovascular Case Reports, 2018
A dual left anterior descending artery (LAD) system where the short LAD arises from the left main coronary artery (LMCA) directly, while the long LAD arises from the bifurcation of the LMCA, is a rare finding.
Suheil Dhanse   +3 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

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