Results 51 to 60 of about 1,649,596 (282)
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Linear Lag Models and Measurements of the Lag Correction Factors
IEEE Access, 2022 For fluoroscopic imaging, flat-panel dynamic detectors can acquire X-ray image sequences with frame rates higher than 300 frames per second. However, the sequentially acquired images have artifacts due to the lag signals, which are caused from trapping ...
Eunae Lee, Dong Sik Kim
doaj +1 more source
, 2007 Any model of tides is based on a specific hypothesis of how lagging depends on the tidal-flexure frequency. For example, Gerstenkorn (1955), MacDonald (1964), and Kaula (1964) assumed constancy of the geometric lag angle, while Singer (1968) and Mignard (
Bills +29 more
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Development of Delpazolid for the Treatment of Tuberculosis
Applied Sciences, 2020 A novel oxazolidinone with cyclic amidrazone, delpazolid (LCB01-0371), was synthesized by LegoChem BioSciences, Inc. (Daejeon, Korea). Delpazolid can improve the minimum bactericidal concentration of Mycobacterium tuberculosis H37Rv and significantly ...
Young Lag Cho, Jichan Jang
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Simultaneous EUV and X-ray variability of NGC 4051 [PDF]
, 1999 We present a flux variability study of simultaneous RXTE and EUVE observations of the highly variable Seyfert galaxy NGC4051. We find a strong correlation between variability in the EUV and medium energy X-ray bands,indicating that both are sampling the ...
A. Fruscione +36 more
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Impact of lag information on network inference [PDF]
, 2018 Extracting useful information from data is a fundamental challenge across disciplines as diverse as climate, neuroscience, genetics, and ecology. In the era of ``big data'', data is ubiquitous, but appropriated methods are needed for gaining reliable ...
Masoller, Cristina, Rubido, Nicolas
core +3 more sources
A thermoelastic micro‐elongated layer under the effect of gravity in the context of the dual‐phase lag model [PDF]
, 2021 Mohamed I. A. Othman +3 more
openalex +1 more source