Results 51 to 60 of about 329,570 (293)
1470 Combining the antigen-presenting cell activator eftilagimod alpha (soluble LAG-3) and pembrolizumab: efficacy results from the 1st line non-small cell lung cancer cohort of TACTI-002 (Phase II) [PDF]
, 2022 Wade T. Iams +19 more
openalex +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Poljoprivreda, 2018 Cilj je rada usporediti raspoloživost i korištenje razvojnih resursa u poljoprivredi te, posljedično, ocijeniti razvojni potencijal poljoprivrede i povezanih djelatnosti na području odabranih jedinica lokalne samouprave Ličko-senjske županije ...
Ivana Starčević +3 more
doaj +1 more source
Respiratory Research, 2020 Epidemiological studies have found strong associations between air pollution and respiratory effects including development and/or exacerbation of asthma and chronic obstructive pulmonary disease (COPD) as well as increased occurrence of respiratory ...
Marit Låg +3 more
doaj +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Spanish Journal of Agricultural Research, 2015 Energy crops cultivation is expected to further increase, which represents an opportunity to establish synergies able to enhance key environmental components (i.e. soil).
Alfonso J. Lag-Brotons, Ignacio Gómez
doaj +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Evaluation of binocular function among pre- and early-presbyopes with asthenopia
Clinical Optometry, 2018 William Reindel,1 Lening Zhang,1 Joseph Chinn,2 Marjorie Rah1 1Vision Care, Bausch & Lomb Inc, Rochester, NY, 2J Chinn LLC, Lafayette, CO, USA Purpose: Individuals approaching presbyopia may exhibit ocular symptoms as they contend with visual demands
Reindel W, Zhang L, Chinn J, Rah M
doaj
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Frontiers in Public HealthIntroductionAs global fertility rates decline, exploring the root causes of birth defects (BDs) becomes urgent. Air pollution, with its ability to penetrate the placental barrier as exogenous toxins, has garnered notable attention in this regard ...
Wen Sun +14 more
doaj +1 more source