Results 51 to 60 of about 1,587,709 (329)
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
Integral motives, relative Krull-Schmidt principle, and Maranda-type theorems [PDF]
, 2014 In the present article we investigate properties of the category of the integral Grothendieck-Chow motives over a field. We discuss the Krull-Schmidt principle for integral motives, provide a complete list of the generalized Severi-Brauer varieties with ...
Semenov, Nikita, Zhykhovich, Maksim
core
Development of Delpazolid for the Treatment of Tuberculosis
Applied Sciences, 2020 A novel oxazolidinone with cyclic amidrazone, delpazolid (LCB01-0371), was synthesized by LegoChem BioSciences, Inc. (Daejeon, Korea). Delpazolid can improve the minimum bactericidal concentration of Mycobacterium tuberculosis H37Rv and significantly ...
Young Lag Cho, Jichan Jang
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
Nonlinear Lag Correction Based on the Autoregressive Model for Dynamic Flat-Panel Detectors
IEEE Access, 2023 Lag signal problems occur in acquiring X-ray image sequences from dynamic flat-panel detectors due to amorphous pixel photodiodes and incomplete readouts.
Eunae Lee, Dong Sik Kim
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Transition from anticipatory to lag synchronization via complete synchronization in time-delay systems [PDF]
, 2005 The existence of anticipatory, complete and lag synchronization in a single system having two different time-delays, that is feedback delay $\tau_1$ and coupling delay $\tau_2$, is identified.
A. S. Pikovsky +8 more
core +2 more sources
Molecular Oncology, EarlyView.Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan +10 more
wiley +1 more source
Generic algebras: rational parametrization and normal forms [PDF]
, 2015 For every algebraically closed field $\boldsymbol k$ of characteristic different from $2$, we prove the following: (1) Generic finite dimensional (not necessarily associative) $\boldsymbol k$-algebras of a fixed dimension, considered up to isomorphism,
Popov, Vladimir L.
core
The changing X-ray time lag in MCG-6-30-15 [PDF]
, 2014 MCG-6-30-15 is one of the most observed Narrow Line Seyfert 1 galaxies in the X-ray band. In this paper we examine the X-ray time lags in this source using a total of 600 ks in observations (440 ks exposure) taken with the XMM-Newton telescope (300 ks in
Alston, W. +8 more
core +1 more source