Results 111 to 120 of about 22,828,036 (302)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Lag Length Selection for Unit Root Tests in the Presence of Nonstationary Volatility [PDF]

A number of recently published papers have focused on the problem of testing for a unit root in the case where the driving shocks may be unconditionally heteroskedastic.
Stephan Smeekes, Peter C.B. Phillips, A.M. Robert Taylor, Giuseppe Cavaliere   +3 more
core   +2 more sources

What do critical reading strategies look like? Eye-tracking and lag sequential analysis reveal attention to data and reasoning when reading conflicting information

Comput. Educ., 2022
Meng‐Jung Tsai, An‐Hsuan Wu, Ivar Bråten, Ching-Yeh Wang   +3 more
semanticscholar   +1 more source

From the help desk: Polynomial distributed lag models [PDF]

Polynomial distributed lag models (PDLs) are finite-order distributed lag models with the impulse-response function constrained to lie on a polynomial of known degree.
Allen McDowell
core  

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Comparative Analysis of Random Forest and Long Short-Term Memory for Predicting Optical Power Degradation in FTTH Networks

Journal of Applied Informatics and Computing
Fiber-to-the-Home (FTTH) networks are widely used to provide high-speed broadband services, but optical power degradation can reduce network performance and service quality.
Hermansyah Hermansyah, Taufiq Taufiq, Defry Hamdhana, Munirul Ula, Muhammad Ikhwanus   +4 more
doaj   +1 more source

How does dialogic teaching facilitate students' creative thinking? Evidence from a sequential analysis of teacher–student dialogue in primary language classrooms

British Educational Research Journal
Dialogic teaching has been shown to be beneficial for students' learning and achievement. However, few studies have investigated how dialogic teaching may foster students' creative thinking in the classroom. This study examined the sequential patterns of
Yang Tao, Deliang Wang, Gao-Wei Chen
semanticscholar   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Infertility grief and filiation experiences 25 years later: detection of multiple cases from the mixed methods approach

Frontiers in Psychology
IntroductionThe diagnosis of infertility generates a significant psychological impact on the couples who experience it. The loss of fertility triggers a psychological mourning process that affects self-esteem and identity.
Núria Camps, Eulàlia Arias-Pujol, Eulàlia Arias-Pujol, M. Teresa Anguera   +3 more
doaj   +1 more source

Identifying Identical Distributed Lag Structures by the Use of Prior SumConstraints [PDF]

This paper derives an estimation procedure which, when the same distributed lag appears twice in an equation to be estimated by least-squares regression, identifies all of the relevant coefficients and lag weights and also constrains the two sets of ...
Benjamin M. Friedman, V. Vance Roley
core