Results 121 to 130 of about 22,828,036 (302)

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Sequential analysis of the interaction between kicker and goalkeeper in penalty kicks

Cuadernos de Psicologia del Deporte
Within the observational methodology, an analysis of the interaction between kickers and goalkeepers has been carried out, in penalty kicks taken in international team competitions, which allows the goalkeeper to obtain relevant information about the ...
José Ramón Barbero, Daniel Lapresa Ajamil, J. Arana, M. Anguera   +3 more
semanticscholar   +1 more source

Sequential Confirmatory Factor Analysis: A Novel Approach to Latent Variable Measurement

Factor score estimation in small sample sizes often encounters parameter bias and convergence failures when constructing hierarchical national/sub-national indices.
Zachary Esses Johnson
core  

Sequential License Buyback Auctions: An Experimental Analysis [PDF]

Fisheries managers use licenses as a method of capping the size of a fishing industry, but as management goals change and the size of fishery stocks fluctuate, managers may be faced with the decision to buy back licenses.
Freeman, Matthew A., Woodward, Richard T.   +1 more
core  

On optimality of kernels for approximate Bayesian computation using sequential Monte Carlo [PDF]

, 2011
Approximate Bayesian computation (ABC) has gained popularity over the past few years for the analysis of complex models arising in population genetics, epidemiology and system biology.
Barnes, C, Chris Barnes, Michael P. H. Stumpf, Sequential Monte Carlo, Julien Cornebise, Stumpf, MPH, Filippi, S, Cornebise, J   +7 more
core  

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Respiratory syncytial virus (RSV) notifications and trends in the transmission cycles from infants and young children to older adults in Ireland: an analysis of incidence shifts over a decade

BMJ Open
Objectives Understanding the epidemiological shifts of respiratory syncytial virus (RSV) is essential to inform public health interventions, particularly given its increased burden on healthcare systems post-COVID-19 pandemic. This study aimed to examine
Roy K Philip, Lisa Domegan, Helen Purtill, Kaushik Mangroo, Natalie Gendy, Eva Kelly, Maureen O’Leary   +6 more
doaj   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Random walks with drift : a sequential approach [PDF]

In this paper sequential monitoring schemes to detect nonparametric drifts are studied for the random walk case. The procedure is based on a kernel smoother.
Steland, Ansgar
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