Results 61 to 70 of about 22,828,036 (302)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Executive Functions Assessment in a Child with Autism: A Pilot Single-Case Study from a Longitudinal and Mixed Methods Approach

open access: yesChildren
Although the literature confirms executive deficits in individuals with autism spectrum disorder (ASD) that hinder adaptation, evidence-based intervention programs targeting this area are scarce, and even fewer have evaluated their effectiveness ...
Marian Acero-Ferrero   +1 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

How Students Use Learning Analytics Dashboards in Higher Education: A Learning Performance Perspective

open access: yesSAGE Open, 2023
Developed to maximize learning performance, learning analytics dashboards (LAD) are becoming increasingly commonplace in education. An LAD’s effectiveness depends on how it is used and varies according to users’ academic levels.
Li Chen   +4 more
doaj   +1 more source

LAG

open access: yes, 2023
In a culture that fetishises technology, speed and convenience, painting seems to lag behind. It's accused of being a throwback to our prehistoric, primordial selves; an indulgence in contemporary life and/ or worse - dead.
Anthony Curran (14734669)
core  

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Compensated Transfer Entropy as a Tool for Reliably Estimating Information Transfer in Physiological Time Series

open access: yesEntropy, 2013
We present a framework for the estimation of transfer entropy (TE) under the conditions typical of physiological system analysis, featuring short multivariate time series and the presence of instantaneous causality (IC).
Alberto Porta   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Multi-Lag Analysis of Symbolic Entropies on EEG Recordings for Distress Recognition

open access: yesFrontiers in Neuroinformatics, 2019
Distress is a critical problem in developed societies given its long-term negative effects on physical and mental health. The interest in studying this emotion has notably increased during last years, being electroencephalography (EEG) signals preferred ...
Arturo Martínez-Rodrigo   +9 more
doaj   +1 more source

An effective method for the explicit solution of sequential problems on the real line

open access: yes, 2017
A general method for solving optimal stopping problems for continuous-time Markov processes on the real line is developed. The basic idea is to first study an auxiliary problem for the two-dimensional process consisting of the underlying Markov process ...
Sören Christensen, Christensen, Sören,
core   +1 more source

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