Results 71 to 80 of about 562,892 (309)

Nonlinear temperature response of lake ice breakup [PDF]

, 2004
A uniquely comprehensive set of four decades of ice breakup data from 196 Swedish lakes covering 13degrees of latitude (55.7degrees N to 68.4degrees N) shows the relationship between the timing of lake ice breakup and air temperature to be an arc cosine ...
Livingstone, David M., Meili, Markus, Weyhenmeyer, Gesa   +2 more
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Ice phenomena on Lake Wielki Staw in the Valley of Five Polish Lakes

Limnological Review, 2017
The paper presents an analysis of the ice phenomena on Lake Wielki Staw in the Valley of Five Polish Lakes based on observations of the Institute of Meteorology and Water Management conducted in the years 1971–1979.
Choiński Adam
doaj   +1 more source

Catastrophic ice lake collapse in Aram Chaos, Mars

, 2014
Hesperian chaotic terrains have been recognized as the source of outflow channels formed by catastrophic outflows. Four main scenarios have been proposed for the formation of chaotic terrains that involve different amounts of water and single or multiple
Kleinhans, Maarten G., Oosthoek, Jelmer H. P., Roda, Manuel, Zegers, Tanja E.   +3 more
core   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Interrelationship Between Nutrients and Chlorophyll-a in an Urban Stormwater Lake During the Ice-covered Period [PDF]

, 2017
Urban stormwater lakes in cold regions are ice-covered for substantial parts of the winter. It has long been considered that the ice-covered period is the “dormant season,” during which ecological processes are inactive.
Chu, K. (Kejian), Davies, E. (Evan), Kemp, J. (Jeff), Loewen, M. (Mark), She, Y. (Yuntong)   +4 more
core   +3 more sources

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Hazard assessment of glacial lake outburst floods from Kyagar glacier, Karakoram mountains, China [PDF]

, 2014
Kyagar glacier is located in the Chinese Karakoram mountains. The glacier tongue entirely blocks the riverbed in the upper Shaksgam valley and impounds a glacial lake, which was the source of several violent and disastrous glacial lake outburst floods ...
Ao, Zhigang, Haemmig, Christoph, Hess, Josef, Huss, Matthias, Keusen, Hansrudolf, Kulubayi, Wubuli, Wegmüller, Urs   +6 more
core   +1 more source

Lake ice ablation rates from permanently ice-covered Antarctic lakes [PDF]

Journal of Glaciology, 2013
AbstractIn the McMurdo Dry Valleys of Antarctica, three large, permanently ice-covered, closed-basin lakes exist along the floor of Taylor Valley. Lake ice ablation (loss of ice mass) is calculated as the sum of sublimation and surface melt, and is the driver of ice-cover turnover in these systems.
H.A. Dugan, M.K. Obryk, P.T. Doran
openaire   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source