Results 51 to 60 of about 562,892 (309)

Remote sensing of lake ice phenology in Alaska

Environmental Research Letters, 2021
The timing of lake ice breakup and freezeup are important indicators of climate change in Arctic and boreal regions because they respond rapidly and directly to variations in climate conditions.
Shuai Zhang, Tamlin M Pavelsky, Christopher D Arp, Xiao Yang   +3 more
doaj   +1 more source

Application of a simple model for ice growth to the Lake St. Moritz, Switzerland

Journal of Glaciology, 2023
We present a Simple Lake Ice Model to calculate the growth rate of lake ice in a cold and relatively dry climate. The focus is on Lake St. Moritz, Switzerland, which has an area of 0.78 km2 and is about 45 m deep.
Johannes Oerlemans, Felix Keller
doaj   +1 more source

InSAR observations of ice elevation and velocity fluctuations at the Flade Isblink ice cap, eastern North Greenland [PDF]

, 2010
The 8500 km(2) Flade Isblink ice cap (FIIC) (81 degrees 15'N, 15 degrees 0'W) is the largest ice cap in Greenland. We use repeat-pass interferometric synthetic aperture radar (InSAR) techniques to investigate the form and flow of the FIIC.
Andrew Shepherd, Atwood, Aud Sundal, Bartholomew, Bingham, Boon, Brenner, Dall, Das, DiMarzio, DiMarzio, Eero Rinnem, Gens, Goldstein, Hall, Helk, Higgins, Hoen, Iken, Iken, Joughin, Joughin, Joughin, Joughin, Kelly, Koch, Krabill, Kwok, Maidment, Massonnet, Mikkelsen, Mohr, Paterson, Peter Nienow, Pritchard, Rignot, Rosen, Scharroo, Schutz, Shepherd, Shepherd, Steffen, Steven J. Palmer, Werner, Zwally, Zwally, Zwally   +46 more
core   +1 more source

Snow and ice on Bear Lake (Alaska) – sensitivity experiments with two lake ice models

Tellus A: Dynamic Meteorology and Oceanography, 2012
Snow and ice thermodynamics of Bear Lake (Alaska) are investigated with a simple freshwater lake model (FLake) and a more complex snow and ice thermodynamic model (HIGHTSI). A number of sensitivity experiments have been carried out to investigate the influence of snow and ice parameters and of different complexity on the results. Simulation results are
Semmler, Tido, Cheng, Bin, Yang, Yu, Rontu, Laura   +3 more
openaire   +3 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Regional Variability and Drivers of Below Ice CO2 in Boreal and Subarctic Lakes [PDF]

, 2015
Northern lakes are ice-covered for considerable portions of the year, where carbon dioxide (CO2) can accumulate below ice, subsequently leading to high CO2 emissions at ice-melt.
Denfeld, Blaize A., Kortelainen, Pirkko, Rantakari, Miitta, Sobek, Sebastian, Weyhenmeyer, Gesa A.   +4 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Ice Thickness Assessment of Non-Freshwater Lakes in the Qinghai–Tibetan Plateau Based on Unmanned Aerial Vehicle-Borne Ice-Penetrating Radar: A Case Study of Qinghai Lake and Gahai Lake

Remote Sensing
Ice thickness has a significant effect on the physical and biogeochemical processes of a lake, and it is an integral focus of research in the field of ice engineering.
Huian Jin, Xiaojun Yao, Qixin Wei, Sugang Zhou, Yuan Zhang, Jie Chen, Zhipeng Yu   +6 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source