Results 71 to 80 of about 198,315 (312)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Correlations of chemical weathering indicators with major chemical constituents in sediments to obtain palaeoclimate information from Chaohu Lake, China

Scientific Reports
The main chemical compositions of 201 surface sediments and 53 deep sediment samples from Chaohu Lake, China, were analysed. Since the surface sediments (0–2 cm depth) in Chaohu Lake are modern sediments, this paper mainly focuses on the deep sediments ...
Ming Huang, Ya-nan Liu, Fu-rong Chen, Yong Tao, Ya-min Sun   +4 more
doaj   +1 more source

Tuning the Dielectric Properties of Individual Clay Nanosheets by Interlayer Composition: Toward Nano‐Electret Materials

Advanced Functional Materials, EarlyView.
The dielectric properties of clays are studied on the level of individual monolayers and functional double stacks. The material breakdown characteristics and charge storage performance are analyzed. For illustration, a defined charge pattern representing a cuneiform character is produced, written into a microscopic clay tile, referencing the origins of
Sebastian Gödrich, Paul Markus, Matthias Stöter, Bernhard Biersack, Rainer Schobert, Josef Breu, Georg Papastavrou   +6 more
wiley   +1 more source

Radiochronology of lake sediments [PDF]

Pure and Applied Chemistry, 1997
Abstract
openaire   +2 more sources

Birth, life and death of the Pannonian Lake [PDF]

, 1990
The Miocene-Pliocene Pannonian Lake formed in an extensional basin system behind the compressional arc of the Carpathians. Its size and depth were comparable to those of the Caspian Sea.
Kázmér, Miklós
core   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Sporormiella as a tool for detecting the presence of large herbivores in the Neotropics [PDF]

, 2016
The reliability of using the abundance of Sporormiella spores as a proxy for the presence and abundance of megaherbivores was tested in southern Brazil. Mud-water interface samples from nine lakes, in which cattle-use was categorized as high, medium, or ...
ABSY ML, Alexandra M. Folcik, APTROOT A, AUGUSTINE DJ, BAKER AG, BAKKER ES, BARNOSKY AD, BORRERO LA, BURNEY DA, COLINVAUX P.A., COLINVAUX PA, COLINVAUX PA, Crystal H. McMichael, DAVIS OK, DAVIS OK, DAVIS OK, DOUGHTY CE, ETIENNE D, FAEGRI K, FROYD CA, GELMAN A, GILL JL, GILL JL, GILL JL, GILL JL, GOODLAND R, GRAYSON DK, JOHNSON CN, JOHNSON CN, JOHNSON CN, LEDRU M.-P, LEDRU ML, MACFADDEN BJ, MACPHEE RDE, Marco Felipe Raczka, Mark B. Bush, MARTIN PS, MARTIN PS, MARTIN PS, MCNAUGHTON SJ, MILLER GH, MORELLATO LPC, PARKER NE, RAPER D, RAUP D.M, RAUP DM, RIPPLE W.J, ROBINSON GS, SMITH FA, STOCKMARR J, VAN GEEL B, WEBB SD, WOOD JR   +52 more
core   +3 more sources

Multiple Twinning in Nacre and Aragonite

Advanced Functional Materials, EarlyView.
Electron backscatter diffraction map of a cluster of geologic aragonite, exhibiting single, double, and triple twins. The whole cluster is approximately 2 cm wide. Colors indicate crystal orientations, so that pixels where the a‐, b‐, and c‐axis is perpendicular to the image plane are green, red, and blue, respectively.
Connor A. Schmidt, William O. Nachlas, Bil Schneider, Xiaoming Mao, Eric Tambutté, Alexander A. Venn, Sylvie Tambutté, Pupa U. P. A. Gilbert   +7 more
wiley   +1 more source

Assessing the spatial and temporal variability and related environmental risks of toxic metals in Lake Asejire, south-western Nigeria

Scientific African, 2020
Lake Asejire in Nigeria is polluted with untreated effluent from nearby aquacultural, urban, agricultural and industrial zones. The metal laden effluent pose a hazard to the health of fish and fish consumers in the lake.
Beaven Utete, Bernadette.T. Fregene
doaj   +1 more source

Colloidal Crack Sintering Lithography for Light‐Induced Patterning of Particle Assemblies

Advanced Functional Materials, EarlyView.
Colloidal crack sintering lithography (CCSL) is a microfabrication technique that uses light‐induced photothermal heating to trigger sintering and controlled cracking in polymer colloidal assemblies. Local structural changes generate microchannels and patterns, enabling direct writing of diverse topographic motifs.
Marius Schoettle, Ariane V. Mader, Willem L. Noorduin   +2 more
wiley   +1 more source