Clinical characteristics, biomarkers and prevalence of cerebral amyloid angiopathy in Alzheimer’s disease: Applying the Boston criteria v2.0 in a memory clinic population [PDF]
Abstract Background Diagnosing cerebral amyloid angiopathy (CAA) is essential when determining Alzheimer's disease (AD) patients’ eligibility for anti‐amyloid immunotherapy since CAA is associated with amyloid‐related imaging abnormalities. The Boston criteria are widely used in memory clinics to identify older adults with a high probability of CAA ...
Lalive H +8 more
europepmc +4 more sources
Pro-Inflammatory c-Met<sup>+</sup> CD4 T Cells in Multiple Sclerosis. [PDF]
Objective Hepatocyte growth factor (HGF) binds exclusively the c‐Met surface receptor, and the HGF/c‐Met axis regulates T cell function in autoimmune diseases. We analyzed c‐Met expression on human CD4 T cells in the blood and cerebrospinal fluid (CSF) from patients with multiple sclerosis (MS) versus non‐inflammatory neurological disease (NIND), to ...
Breville G +6 more
europepmc +2 more sources
Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age- and BMI-Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response. [PDF]
ABSTRACT Objective Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age‐ and BMI‐adjusted) with absolute concentrations for the prediction of response to disease‐modifying therapy.
Einsiedler M +43 more
europepmc +2 more sources
Adapting and validating the McCance Brain Care Score for French‐speaking patients: a prospective study on motivation to improve Brain Health in a neurology outpatient clinic [PDF]
Abstract Background Promoting brain health is essential for addressing the growing burden of neurological disorders, with 45% of dementia cases linked to modifiable risk factors. The McCance Brain Care Score (BCS, Figure 1) supports risk reduction by empowering patients to adopt preventive strategies that modify established risk factors.
Lalive H +10 more
europepmc +2 more sources
The effect of leave policies on increasing fertility: a systematic review
Low fertility is set to worsen economic problems in many developed countries, and maternity, paternity, and parental leave have emerged as key pro-natal policies.
Jac Thomas +3 more
doaj +1 more source
We document mental and social distress of children, adolescents and adults, using data on 3 million calls to German helplines between January 2019 and May 2022.
Marius Brülhart +2 more
doaj +1 more source
c-Met is expressed by highly autoreactive encephalitogenic CD8+ cells
Background CD8+ T lymphocytes are critical mediators of neuroinflammatory diseases. Understanding the mechanisms that govern the function of this T cell population is crucial to better understanding central nervous system autoimmune disease pathology. We
Mahdia Benkhoucha +2 more
doaj +1 more source
El dialogo inconcluso Recepción de [PDF]
Este artículo analiza porqué, "El Refugio de las Masas" de Christian Lalive d Epinay, y los aportes valiosos del autor, fueron conocidos y comentados hasta algunos años después de su publicación.
Dr. Carlos Garma Navarro
doaj
En la introducción de este voluminoso texto los autores definen el objetivo de este libro: "Reunir en una misma publicación aquellos trabajos que simbolizan, en sus diferencias y congruencias, la consolidación de una temática que se gestó en paralelo a ...
Bernardo Guerrero Jiménez
doaj +1 more source
Update on multiple sclerosis treatments
Relapsing-remitting multiple sclerosis (RRMS) management has dramatically changed over the past decade. New drugs have arrived on the market, allowing for more individualised treatment selection.
Claire Bridel, Patrice H. Lalive
doaj +1 more source

