Results 41 to 50 of about 588,680 (286)
Frontiers in MicrobiologyThe CRISPR-Cas system, an adaptive immune mechanism in prokaryotes against bacteriophages, has been developed into a versatile tool for recognizing and cleaving target nucleic acid sequences.
Chan Kyeong Lee +3 more
doaj +1 more source
Stochastic Variational Search for $^{4}_{\Lambda\Lambda}$H
, 2003 A four-body calculation of the $pn\Lambda\Lambda$ bound state, $^{\ 4}_{\Lambda\Lambda}$H, is performed using the stochastic variational method and phenomenological potentials.
A. Nogga +18 more
core +1 more source
Nonhuman Primate Induced Pluripotent Stem Cells in Regenerative Medicine
Stem Cells International, 2012 Among the various species from which induced pluripotent stem cells have been derived, nonhuman primates (NHPs) have a unique role as preclinical models.
Yuehong Wu +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Morphometry of Superior Sagittal Sinus and Its Clinical Significance
Indian Journal of NeurosurgeryThe position of the superior sagittal sinus (SSS) in the midline along the sagittal suture is still a debate among neurosurgeons. The aim of the study is to evaluate the diameter and deviation of the SSS at various landmarks in the midline.
Grace Suganya +4 more
doaj +1 more source
Meteorological Applications, 2021 Building risk models for present‐day climate requires an understanding of recent climate trends. To estimate the climate change driven component of recent rainfall trends in Europe, we introduce a novel methodology for combining trend estimates from ...
Stephen Jewson +2 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Spectral Gaps of Almost Mathieu Operator in Exponential Regime [PDF]
, 2013 For almost Mathieu operator $(H_{\lambda,\alpha,\theta}u)_n=u_{n+1}+u_{n-1}+2\lambda \cos2\pi(\theta+n\alpha)u_n$, the dry version of Ten Martini problem predicts that the spectrum $\Sigma_{\lambda,\alpha}$ of $ H_{\lambda,\alpha,\theta}$ has all gaps ...
Liu, Wencai, Yuan, Xiaoping
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Dose-Response, 2014 P53 protein has an intrinsic role in modulating the cellular response against DNA radioinduced damages and has been pointed out as an indirect indicator of individual radiosensitivity.
Rafael de Freitas e Silva +3 more
doaj +1 more source