Results 51 to 60 of about 717,080 (383)
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Ecosphere, 2017 Animal resource requirements differ among life‐history stages, and thus, habitat is most appropriately thought of as specific to a particular life stage.
Kristin Kane +4 more
doaj +1 more source
Bipolar complex fuzzy semigroups
AIMS Mathematics, 2023 The notion of the bipolar complex fuzzy set (BCFS) is a fundamental notion to be considered for tackling tricky and intricate information. Here, in this study, we want to expand the notion of BCFS by giving a general algebraic structure for tackling ...
Ubaid Ur Rehman +2 more
doaj +1 more source
$^{6}_{\Lambda\Lambda}$He and $^{10}_{\Lambda\Lambda}$Be hypernuclei calculations with realistic interactions [PDF]
Brazilian Journal of Physics, 2003 We study the $^{6}_{\Lambda\Lambda}$He and $^{10}_{\Lambda\Lambda}$Be hypernuclei in the three- and four-body models, respectively, employing harmonic oscillator bases and presently most realistic a-a, a-L and L-L interactions. In order to improve convergence we use correlation functions in the case of $^{10}_{\Lambda\Lambda}$Be.
openaire +4 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Double-Lambda hypernuclei within a Skyrme-Hartree-Fock approach
, 2014 We extend our Skyrme-Hartree-Fock (SHF) approach, which was used earlier to describe successfully the single-$\Lambda$ hypernuclei, to investigate the binding and the $\Lambda \Lambda$ bond energies of the double-$\Lambda$ hypernuclei.
Dhiman, Shashi K. +2 more
core +1 more source
FEBS Letters, EarlyView.Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel +2 more
wiley +1 more source
$A$--Dependence of $\Lambda\Lambda$ Bond Energies in Double---$\Lambda$ Hypernuclei
, 1995 The $A$-dependence of the bond energy $\Delta B_{\Lambda\Lambda}$ of the ${\Lambda\Lambda}$ hypernuclear ground states is calculated in a three-body ${\Lambda + \Lambda + {^{A}Z}}$ model and in the Skyrme-Hartree-Fock approach. Various ${\Lambda\Lambda}$
Andrey M. Shirokov +28 more
core +1 more source
Superdeformed $\Lambda$ hypernuclei with antisymmetrized molecular dynamics [PDF]
, 2014 The response to the addition of a $\Lambda$ hyperon is investigated for the deformed states such as superdeformation in $^{41}_\Lambda$Ca, $^{46}_\Lambda $Sc and $^{48}_\Lambda$Sc. In the present study, we use the antisymmetrized molecular dynamics (AMD)
Fukukawa, Kenji +5 more
core +2 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source