Results 51 to 60 of about 585,996 (284)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

On the grade of modules over Noetherian rings

open access: yes, 2007
Let $\Lambda$ be a left and right noetherian ring and $\mod \Lambda$ the category of finitely generated left $\Lambda$-modules. In this paper we show the following results: (1) For a positive integer $k$, the condition that the subcategory of $\mod ...
Huang, Zhaoyong
core   +2 more sources

A dual graph construction for higher-rank graphs, and $K$-theory for finite 2-graphs [PDF]

open access: yes, 2004
Given a $k$-graph $\Lambda$ and an element $p$ of $\NN^k$, we define the dual $k$-graph, $p\Lambda$. We show that when $\Lambda$ is row-finite and has no sources, the $C^*$-algebras $C^*(\Lambda)$ and $C^*(p\Lambda)$ coincide.
Allen, Stephen, Pask, David, Sims, Aidan
core   +3 more sources

Double $\Lambda$ and the $\Lambda-\Lambda$ Interaction

open access: yes, 1997
The $\Lambda$-$\Lambda$ effective interaction, in the channel $L=S=0$, in the nuclear medium is fitted to the available binding energies, $B_{\Lambda\Lambda}$, of double $\Lambda$ hypernuclei: $^{6}_{\Lambda\Lambda}$He, $^{10}_{\Lambda\Lambda}$Be and $^{13}_{\Lambda\Lambda}$B. The mesonic decay of these hypernuclei is also investigated.
Caro, J.   +2 more
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Simultaneous Analysis of P53 Protein Expression and Cell Proliferation in Irradiated Human Lymphocytes by Flow Cytometry

open access: yesDose-Response, 2014
P53 protein has an intrinsic role in modulating the cellular response against DNA radioinduced damages and has been pointed out as an indirect indicator of individual radiosensitivity.
Rafael de Freitas e Silva   +3 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Wild Horse Demography: Implications for Sustainable Management Within Economic Constraints

open access: yesHuman-Wildlife Interactions, 2018
Management of wild horse (Equus ferus caballus ) populations on western U.S. rangelands has been a challenge since horses were given legal protection through the passage of the Wild Free-Roaming Horses and Burros Act (WFRHBA) in 1971.
Robert A. Garrott
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Development of a Diesel Engine Thermal Overload Monitoring System with Applications and Test Results

open access: yesEnergies, 2017
In this research, the development of a diesel engine thermal overload monitoring system is presented with applications and test results. The designed diesel engine thermal overload monitoring system consists of two set of sensors, i.e., a lambda sensor ...
Sangram Kishore Nanda   +3 more
doaj   +1 more source

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