Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Maternal dietary citrulline supplementation increases fetal growth and programs pancreatic development in the lambs. [PDF]
Herring AB +4 more
europepmc +1 more source
MRI in Sheep Model for Myelomeningocele Repair Using a Novel Polymer and Other Dural Patches
ABSTRACT Objective To compare postnatal MRI outcomes after prenatal myelomeningocele repair using three different dural substitutes. Method 32 sheep fetuses were included, with 34.3%(11/32) serving as healthy controls and the remaining undergoing prenatal spinal lumbar defect creation to recreate a myelomeningocele in the fetus.
Usha D. Nagaraj +5 more
wiley +1 more source
Effects of Dietary <i>Salvia sclarea</i> L. Extract Supplementation on the Gut Microbiota, and Serum Metabolome in Lambs. [PDF]
Ma X, Nan S, Zhang L, Xue Y, Zhang W.
europepmc +1 more source
Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward
Organ Medicine, EarlyView.
Xiaoyu Gan +3 more
wiley +1 more source
Made in the shade: Leaf responses of native wildflowers to single‐axis photovoltaic solar energy
As solar energy expands globally, balancing renewable power generation with biodiversity and ecosystem health has become an urgent challenge. This study investigated how native wildflowers respond at leaf level to the unique microclimates created by rotating solar panels in California's Central Valley.
Yudi Li +3 more
wiley +1 more source
Effects of an Essential Oil Blend on In Vitro Methane Production, In Vitro and In Vivo Nutrient Digestibility, Growth Performance, and Meat Quality in Lithuanian Blackface Lambs. [PDF]
Lileikis T +3 more
europepmc +1 more source
From wild to tamed: Reimagining novel crops through omics and local plant diversity
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá +1 more
wiley +1 more source
The effects of supplementing Astragalus and fermented Astragalus on lactation performance, rumen microbiota, and lamb weight gain in Turpan black sheep. [PDF]
Lu H +15 more
europepmc +1 more source

