Results 51 to 60 of about 50,551 (154)

Review of Biological Agents in the Therapeutic Management of Monogenic Genodermatoses

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Monogenic genodermatoses encompass a diverse group of over 400 distinct disorders, presenting significant therapeutic challenges. Recent advancements in the clinical application of biological agents have heralded a new era in the management of these conditions.
Xueying Wang, Qing Zhao, Hong Liu, Furen Zhang, Zhiqiang Song   +4 more
wiley   +1 more source

Clinico-epidemiological study of congenital ichthyosis in a tertiary care center of Eastern India

Indian Journal of Dermatology, 2017
Background: Congenital ichthyoses comprises various specific genetic diseases and can range from mild to very severe presentation. Furthermore, these may be associated with various syndromes.
Arghyaprasun Ghosh, Rahul Ahar, Gobinda Chatterjee, Neha Sharma, Shruti Alhad Jadhav   +4 more
doaj   +1 more source

Two- and three-dimensional sonographic findings of harlequin ichthyosis: case report and literature review

Anais Brasileiros de Dermatologia, 2023
Background Harlequin ichthyosis (HI) is a rare skin disorder with extremely high lethality due to a mutation of the ABCA12 gene. Because of its rarity and the often-late onset, prenatal screening for HI is extremely difficult, and most pregnant women ...
Zesi Liu, Chunli Jing
doaj   +1 more source

The Impact of Age on the Lipidomic Profile of the Stratum Corneum and Associated Effects on Structure, Function and Overall Skin Health in Adults Predisposed to Atopic Dermatitis

Experimental Dermatology, Volume 34, Issue 12, December 2025.
Advancing age in eczema‐prone adults correlates with increased dryness, reduced hydration and altered lipid profiles. Spectroscopy showed declines in lipids, water, esters and carboxylates. Lipidomics revealed rising ceramide species, shorter acyl chains and TAG associations.
S. F. Williams, P. Andrew, K. Brown, J. Chittock, A. Pinnock, A. Poyner, M. J. Cork, S. G. Danby   +7 more
wiley   +1 more source

A rare case of ocular pterygium in a young boy with congenital lamellar ichthyosis

Indian Journal of Ophthalmology. Case Reports
Congenital lamellar ichthyosis is a rare dermato-ocular disease occurring in 1:300,000 population and is autosomal recessive. The most common ocular manifestation reported is cicatricial ectropion.
Shubratha S Hegde, Sandhya Dharwadkar, K Athira, Harsha Shaji   +3 more
doaj   +1 more source

PEG‐23 glyceryl distearate, a multifunctional skin‐supporting material, upregulates the expression of factors associated with epidermal barrier and hydration

International Journal of Cosmetic Science, Volume 47, Issue 6, Page 1056-1069, December 2025.
Polyethylene glycol‐23 glyceryl distearate (GDS‐23) forms niosomes and penetrates the skin. Our results suggest that the pharmacological effects following dermal penetration of GDS‐23 may enhance skin homeostasis by improving barrier function and moisture retention.
Tatsuro Miyoshi, Brian C. Keller, Sui Nakagawa, Takashi Ashino, Satoshi Numazawa   +4 more
wiley   +1 more source

Autosomal recessive ichthyosis with limb reduction defect: A simple association and not CHILD syndrome

Egyptian Journal of Medical Human Genetics, 2016
Ichthyosis is a genetically and phenotypically heterogeneous disease that can be isolated and restricted to the skin manifestations or associated with extracutaneous symptoms.
Rabah M. Shawky, Solaf M. Elsayed, Heba Amgad   +2 more
doaj   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

A Rare Familial Case of Harlequin Ichthyosis in an Infant of a Diabetic Mother: A Diagnostic and Management Challenge in Low and Middle Income Settings

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Harlequin Ichthyosis (HI) is an extremely rare, autosomal recessive, and highly fatal condition in neonates. It is especially difficult to control in the low‐ and middle‐income countries (LMICs) due to the low rate of prenatal screening, cultural reluctance, and lack of access to neonatal intensive care.
Muhammad Zaeem, Ameer Hamza Mehmood Ul Hassan, Muhammad Hassaan Javaid, Muhammad Usman, Muhammad Ahmed, Muhammad Usama Naveed, Mohammad Yassin Al Aboud   +6 more
wiley   +1 more source

Early Neonatal Death in Harlequin Ichthyosis: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Harlequin ichthyosis is a rare, life‐threatening neonatal disorder often mistaken for collodion baby. We report a 37‐week neonate with severe ectropion, eclabium, and thick fissured scales who died on Day 2 despite optimal care. This case highlights the diagnostic challenges, intensive management needs, and poor prognosis of Harlequin ...
Ahmed Alanzi, Dawood Alatefi, Malik Alkabazi, Bano Alsaleh, Amir Fouad, Islam Al Oraby   +5 more
wiley   +1 more source