Results 121 to 130 of about 371,037 (309)

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

Creep and creep rupture of laminated graphite/epoxy composites [PDF]

An incremental numerical procedure based on lamination theory is developed to predict creep and creep rupture of general laminates. Existing unidirectional creep compliance and delayed failure data is used to develop analytical models for lamina response.
Brinson, H. F., Dillard, D. A., Morris, D. H.   +2 more
core   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types

eLife
Notch signaling is an evolutionarily conserved pathway for specifying binary neuronal fates, yet how it specifies different fates in different contexts remains elusive.
Chundi Xu, Tyler B Ramos, Owen J Marshall, Chris Q Doe   +3 more
doaj   +1 more source

Ingrowth by photoreceptor axons induces transcription of a retrotransposon in the developing Drosophila brain [PDF]

, 1994
The development of the lamina, the first optic ganglion of the fly visual system, depends on inductive cues from the innervating photoreceptor axons. lacZ expression from a P-element insertion, A72, occurs in the anlage of the lamina coincident with axon
Benzer, Seymour, Mozer, Brian A.
core  

The Shapes of Flux Domains in the Intermediate State of Type-I Superconductors

, 1997
In the intermediate state of a thin type-I superconductor magnetic flux penetrates in a disordered set of highly branched and fingered macroscopic domains.
A. B. Pippard, A. Bodmer, A. Bodmer, A. Cebers, A. Fortini, A. Hagberg, A. J. Dickstein, A. Kashuba, A. Kashuba, A. L. Fetter, A. O. Tsebers, A. T. Dorsey, Alan T. Dorsey, Ar. Abanov, C. A. Duran, C. B. Muratov, C. Flament, C. Kooy, D. A. Kessler, D. Andelman, D. J. E. Callaway, D. M. Petrich, D. P. Jackson, E. R. Andrew, F. Haenssler, F. Liu, G. Birkhoff, G. Lasher, H. Bokil, H. Frahm, I. V. Sharvin, J. A. Cape, J. C. Osborn, J. P. Hurault, J. Pearl, J. S. Nagumo, J. Toner, K. J. Lee, K. J. Lee, K. J. Stine, K. Maki, K. Y. C. Lee, K.-O. Ng, L. D. Landau, M. C. Cross, M. Seul, M. Seul, R. E. Goldstein, R. E. Goldstein, R. E. Goldstein, R. E. Rosensweig, R. FitzHugh, R. FitzHugh, R. N. Goren, R. P. Huebener, R. P. Huebener, R. V. Kohn, Raymond E. Goldstein, S. A. Langer, S. J. Chapman, T. E. Faber, W. Helfrich, W. W. Mullins   +62 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source