Results 31 to 40 of about 97,726 (268)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Comparative CFD Investigation of Laminar and Transition SST Models in a Molten Salt Natural Circulation Loop

open access: yesEnergies
Molten salts are widely used in high-temperature energy systems because of their thermal properties. In such applications, natural circulation provides a passive means of heat transport in systems that require passive safety features.
Benrico Fredi Simamora, Jae Young Lee
doaj   +1 more source

Experimental Analysis of Laminar Flow and Heat Transfer in a Multi-Port Finned Minichannel

open access: yesHittite Journal of Science and Engineering, 2016
D ue to their high heat transfer rate, small scale channels have been a popular area of study for the past three decades, especially for heat exchangers.
Berk Cevrim   +2 more
doaj   +1 more source

A New Approach to Laminar Flowmeters [PDF]

open access: yesSensors, 2010
After studying the performance and characteristics of actual laminar flowmeters a new disposition for this type of sensors is proposed in such a way that the measurement errors introduced by the intrinsic nature of the device can be minimized. The preliminary study shows that the developing entry region introduces non-linearity effects in all these ...
Fernando López-Peña   +3 more
openaire   +4 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov   +2 more
wiley   +1 more source

Laminar ceilings? Shell construction in the work of some masters of modern architecture

open access: yesCuaderno de Notas, 2018
This contribution explores the constructive and formal potential of the laminar structures in the work of three prominent figures of Modern Architecture.
Rafael García García
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

Theoretical and numerical approaches of a plane, laminar and non-confined, impinging jet

open access: yesRevue des Énergies Renouvelables, 2015
We propose in this paper, a numerical study of a planar impacting jet flow. The flow is assumed isothermal, laminar and unconfined. The developed computer code is based on the finite volume method, which was used to discretize the N-S equations. The code
A. Aliouali, K. Talbi, M. Kadja
doaj  

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