Results 101 to 110 of about 4,936,435 (388)

A Novel Microfluidic System for 3D Epidermis and Full‐Thickness Skin Growth for Nanoparticle Safety Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa   +7 more
wiley   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger   +7 more
wiley   +1 more source

Research in Natural Laminar Flow and Laminar-Flow Control, part 2 [PDF]

open access: yes
Part 2 of the Symposium proceedings includes papers addressing various topics in basic wind tunnel research/techniques and computational transitional research.
Hefner, Jerry N., Sabo, Frances E.
core   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi   +7 more
wiley   +1 more source

Effects of Velocity Profiles on Measuring Accuracy of Transit-Time Ultrasonic Flowmeter

open access: yesApplied Sciences, 2019
Ultrasonic wave carries the information for flowing velocity when it is propagating in flowing fluids. Flowrate can be obtained by measuring the propagation time of ultrasonic wave. The principle of transit-time ultrasonic flowmeters used today was based
Hui Zhang, Chuwen Guo, Jie Lin
doaj   +1 more source

Flight experiences with laminar flow [PDF]

open access: yes
A review of natural laminar flow (NLF) flight experiences over the period from the 1930's to the present has been given to provide information on the achievability and maintainability of NLF in typical airplane operating environments. Significant effects
Holmes, Bruce J.
core   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

open access: yesAdvanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente   +5 more
wiley   +1 more source

DIAGNOSIS OF STEADY-STATE CHARACTERISTICS IN LAMINAR FLOW OF FLUIDS

open access: yesRudarsko-geološko-naftni Zbornik
Laminar flow of fluids is one of the most common forms of motion in oilfield practice. In such a flow regime of fluid, the determination of velocity-flow rate performance which takes into account the rheological properties of the fluid is of great ...
Gafar Ismayilov   +2 more
doaj   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

open access: yesAdvanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues   +6 more
wiley   +1 more source

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