Results 21 to 30 of about 105,046 (218)
CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Cell Reports, 2017 Summary: Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition.
Mitchell H. Omar +7 more
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Frontiers in Medicine, 2022 The ocular surface is composed of two phenotypically and functionally different epithelial cell types: corneal and the conjunctival epithelium. Upon injury or disease, ocular surface homeostasis is impaired resulting in migration of conjunctival ...
Tiago Ramos +14 more
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Laminin 511-E8, an autoantigen in IgG4-related cholangitis, contributes to cholangiocyte protection
JHEP ReportsBackground & Aims: IgG4-related cholangitis (IRC) is the hepatobiliary manifestation of IgG4-related disease. Anti-laminin 511-E8 autoantibodies have been identified in its pancreatic manifestation.
David C. Trampert +5 more
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Impairment Mechanisms and Intervention Approaches for Aged Human Neuromuscular Junctions
Frontiers in Molecular Neuroscience, 2020 The neuromuscular junction (NMJ) is a chemical synapse formed between a presynaptic motor neuron and a postsynaptic muscle cell. NMJs in most vertebrate species share many essential features; however, some differences distinguish human NMJs from others ...
Yomna Badawi +2 more
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Tumor Biology, 2017 Laminin γ2 (LAMC2) has been reported to be involved in the development and progression of a variety of tumors. However, its function in human colorectal cancer is unclear. Our study aimed to investigate the role of laminin γ2 in colorectal cancer.
Dandan Huang +4 more
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Anti-laminin-1 Autoantibodies, Pregnancy Loss and Endometriosis
Clinical and Developmental Immunology, 2004 Laminin-1 is a major component and multifunctional glycoprotein of basement membranes that consists of three different subunits, α1, β1 and γ1 chains. It is the earliest synthesized network-forming protein during embryogenesis and
Junko Inagaki +4 more
doaj +1 more source
Cell Reports, 2017 Endothelial basement membranes constitute barriers to extravasating leukocytes during inflammation, a process where laminin isoforms define sites of leukocyte exit; however, how this occurs is poorly understood.
Jian Song +16 more
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Veterinary Sciences, 2022 Benign and malignant nerve sheath tumors (NST) pose a major challenge in routine diagnostic anatomic pathology because of shared histomorphological features with other soft-tissue tumors (STT).
Sílvia Sisó +5 more
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Frontiers in Immunology, 2020 Tumor-infiltrating lymphocytes (TILs) are major players in the immune-mediated control of cancer and the response to immunotherapy. In primary cancers, however, TILs are commonly absent, suggesting T-cell entry into the tumor microenvironment (TME) to be
Diego Martínez-Rey +4 more
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LanB1 Cooperates With Kon-Tiki During Embryonic Muscle Migration in Drosophila
Frontiers in Cell and Developmental Biology, 2022 Muscle development is a multistep process that involves cell specification, myoblast fusion, myotube migration, and attachment to the tendons. In spite of great efforts trying to understand the basis of these events, little is known about the molecular ...
Juan José Pérez-Moreno +6 more
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