Endogenous laminin is required for human airway smooth muscle cell maturation
Respiratory Research, 2006 Background Airway smooth muscle (ASM) contraction underlies acute bronchospasm in asthma. ASM cells can switch between a synthetic-proliferative phenotype and a contractile phenotype.
Tran Thai +4 more
doaj +1 more source
Components of cell-matrix linkage as potential new markers for prostate cancer [PDF]
, 2011 Prostate cancer is one of the most common tumor diseases worldwide. Often being non-aggressive, prostate tumors in these cases do not need immediate treatment.
Eble, Johannes Andreas, Navdaev, Alexey
core +2 more sources
Selection of functional human antibodies from retroviral display libraries [PDF]
, 2004 Antibody library technology represents a powerful tool for the discovery and design of antibodies with high affinity and specificity for their targets.
Urban, Johannes H. +6 more
core +2 more sources
Serum level of laminin in rats fed with a high-fat diet with sulodexide administration
Бюллетень сибирской медицины, 2022 Background. Increased consumption of animal fat with food contributes to the accumulation of lipids both in the blood and in individual cell structures.
O. G. Gileva +2 more
doaj +1 more source
Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]
, 2012 BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Lin, Shuo +2 more
core +1 more source
Cumulative prognostic power of laminin genes in colorectal cancer
BMC Medical Genomics, 2018 Background Laminins are a major family of extracellular matrix proteins and the main component of basement membranes. Laminins are involved in many if not all stages of cancer progression, and expression of laminin genes has prognostic value in various ...
Vladimir V. Galatenko +4 more
doaj +1 more source
Skeletal Muscle, 2020 Background Laminin-α2-related congenital muscular dystrophy (LAMA2-CMD) is a devastating genetic disease caused by mutations in the LAMA2 gene. These mutations result in progressive muscle wasting and inflammation leading to delayed milestones, and ...
Pamela Barraza-Flores +5 more
doaj +1 more source
Amino acid sequence and distribution of mRNA encoding a major skeletal muscle laminin binding protein: an extracellular matrix-associated protein with an unusual COOH-terminal polyaspartate domain. [PDF]
, 1988 Two cDNAs encoding an abundant chicken muscle extracellular matrix (ECM)-associated laminin-binding protein (LBP) have been isolated and sequenced. The predicted primary amino acid sequence includes a probable signal peptide and a site for N-linked ...
Clegg, DO +4 more
core +2 more sources
CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Cell Reports, 2017 Summary: Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition.
Mitchell H. Omar +7 more
doaj +1 more source
Current approaches to the diagnosis of autoimmune bullous dermatoses
Vestnik Dermatologii i Venerologii, 2021 A modern review of highly effective methods for the diagnosis of autoimmune bullous dermatoses are presented. The specificity of the production of autoantibodies underlying bullous dermatoses are described.
Marianna B. Drozhdina +2 more
doaj +1 more source