Results 151 to 160 of about 3,501,652 (356)

Four pocket parks: Towards landed commons

open access: yesUrban Transcripts, 2020
The project of four pocket parks is being carried out in the framework of the sustainable neighbourhood contracts (contrat de quartier durable), an urban renewal policy at regional scale in Brussels, in which regional funds are subsiding communal urban ...
Guillaume Vanneste, Nicolas Willemet
doaj  

The third dimension in landscape metrics analysis applied to Central Alentejo-Portugal [PDF]

open access: yes, 2010
Landscape metrics have been widely developed over the last two decades, although the question remains: How does landscape metrics relates with ecological processes?
Batista, Teresa   +2 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

From Royal Road to Epistatic Road for Variable Length Evolution Algorithm [PDF]

open access: yesLecture notes in computer science (Lect. notes comput. sci.) ISSN 0302-9743 (27/10/2003) 3-14, 2007
Although there are some real world applications where the use of variable length representation (VLR) in Evolutionary Algorithm is natural and suitable, an academic framework is lacking for such representations. In this work we propose a family of tunable fitness landscapes based on VLR of genotypes.
arxiv  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

The COVID-19 vaccine development landscape

open access: yesNature reviews. Drug discovery, 2020
Tung Thanh Le   +6 more
semanticscholar   +1 more source

Inherently trap-free convex landscapes for full quantum optimal control [PDF]

open access: yesarXiv, 2016
We present a comprehensive analysis of the landscape for full quantum-quantum control associated with the expectation value of an arbitrary observable of one quantum system controlled by another quantum system. It is shown that such full quantum-quantum control landscapes are convex, and hence devoid of local suboptima and saddle points that may exist ...
arxiv  

From Landscape Atlas to Flemish Heritage Landscapes: using landscape inventories to formulate landscape quality objectives in a participative process [PDF]

open access: yes, 2011
The European Landscape Convention recommends the realisation of landscape policy, meaning “an expression by the competent public authorities of general principles, strategies and guidelines that permit the taking of specific measures aimed at the ...
Antrop, Marc, Van Eetvelde, Veerle
core   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

open access: yesAging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal   +8 more
wiley   +1 more source

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