Results 41 to 50 of about 1,326,395 (314)

Modern climatic changes of semi-desert landscapes of the Northern Caucasus

open access: yesЮг России: экология, развитие, 2015
The authors of the article reveal trends of climatic conditions changing and variability of hydro-thermal conditions in semidesert landscapes of Northern Caucasus.
Z. V. Ataev, V. V. Bratkov
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Doing the Vimy Glide: Intersections of Landscape, Art, and Memory in Vern Thiessen’s Vimy

open access: yesCaliban: French Journal of English Studies, 2015
Le centenaire de la Première Guerre Mondiale (1914-1918) a suscité un intérêt renouvelé pour les récits de guerre, aussi bien au Canada qu’à travers le monde.
Jan Lermitte
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Remembering Yellowstone: Nature Conservation, Popular Culture and Belonging

open access: yesGeography Notebooks
Yellowstone is globally recognised as the world’s first national park, but the depth of its meaning goes beyond the history of nature conservation. This paper presents the park as an assemblage of landscapes, memories and popular environmental discourses.
Margherita Cisani
doaj   +1 more source

Plymouth Rocks and Christmas Turkeys: from Ecology to Metafiction in Two Short Stories by Alice Munro

open access: yesCaliban: French Journal of English Studies, 2017
Cet article utilise une grille de lecture fondée sur l’écocritique pour analyser la nouvelle intitulée “The Shining Houses,” d’abord diffusée sur CBC Wednesday Night le 6 juin 1962 puis publiée dans le volume Dance of the Happy Shades en 1968 ainsi que ...
Oriana Palusci
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Landscape of Serotypes Pneumococcus Isolate with Pneumococcal Meningitis in the Russian Federation

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Invasive pneumococcal serotypes landscape in various Russian regions studied. The study showed dominance (in decreasing order of importance) serogroups/serotypes 3, 6, 19, 4, 23, 18, 14, 15, 7, 11 and 9, which accounted for 88% of all identified ...
G. V. Beloshitsky   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Landscape research in Belgium

open access: yesBelgeo, 2004
In the federal state Belgium, landscape research evolved from regional geographical monographs to more applied research that focuses upon the specific problems in each of the regions.
Marc Antrop   +5 more
doaj   +1 more source

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