Results 61 to 70 of about 3,116,119 (312)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Doing the Vimy Glide: Intersections of Landscape, Art, and Memory in Vern Thiessen’s Vimy

open access: yesCaliban: French Journal of English Studies, 2015
Le centenaire de la Première Guerre Mondiale (1914-1918) a suscité un intérêt renouvelé pour les récits de guerre, aussi bien au Canada qu’à travers le monde.
Jan Lermitte
doaj   +1 more source

Landscape aesthetics: Assessing the general publics’ rural landscape preferences [PDF]

open access: yes, 2011
working paperThe central aim of this study was to gain greater insights into the factors that affect individuals’ preferences for a variety of landscape settings.
Howley, Peter
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Remembering Yellowstone: Nature Conservation, Popular Culture and Belonging

open access: yesGeography Notebooks
Yellowstone is globally recognised as the world’s first national park, but the depth of its meaning goes beyond the history of nature conservation. This paper presents the park as an assemblage of landscapes, memories and popular environmental discourses.
Margherita Cisani
doaj   +1 more source

Plymouth Rocks and Christmas Turkeys: from Ecology to Metafiction in Two Short Stories by Alice Munro

open access: yesCaliban: French Journal of English Studies, 2017
Cet article utilise une grille de lecture fondée sur l’écocritique pour analyser la nouvelle intitulée “The Shining Houses,” d’abord diffusée sur CBC Wednesday Night le 6 juin 1962 puis publiée dans le volume Dance of the Happy Shades en 1968 ainsi que ...
Oriana Palusci
doaj   +1 more source

Consideration of landscape in the framework documentation during the evolution of the Rural Environment Protection Scheme (REPS) in the Republic of Ireland. [PDF]

open access: yes, 2010
working paperThis paper looks at the changing concept of landscape during the evolution of REPS. It reviews and groups definitions of landscape and identifies their agri-environmental relevance.
Fry, John, green, stuart, Whelan, Jackie
core  

Islands in the landscape [PDF]

open access: yes, 2007
The string theory landscape consists of many metastable de Sitter vacua, populated by eternal inflation. Tunneling between these vacua gives rise to a dynamical system, which asymptotically settles down to an equilibrium state. We investigate the effects
A. Aguirre   +26 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Landscape of Serotypes Pneumococcus Isolate with Pneumococcal Meningitis in the Russian Federation

open access: yesЭпидемиология и вакцинопрофилактика, 2015
Invasive pneumococcal serotypes landscape in various Russian regions studied. The study showed dominance (in decreasing order of importance) serogroups/serotypes 3, 6, 19, 4, 23, 18, 14, 15, 7, 11 and 9, which accounted for 88% of all identified ...
G. V. Beloshitsky   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy