Results 61 to 70 of about 682,231 (268)
Effets paysagers des transformations agricoles et rurales dans le sud du pays d’Auge
In Situ, 2012 Starting out from the commune of Camembert in the pays d’Auge in Normandy, a place which enjoys an archetypal image of a well-preserved piece of countryside, this article sets out to evaluate the effects on the landscape of the modifications in built ...
Philippe Madeline
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Ecology and EvolutionHuman‐induced habitat loss and fragmentation threaten biodiversity in the Eastern Himalayas, a crucial part of the Indo‐Myanmar biodiversity hotspot.
Arif Ahmad, Govindan Veeraswami Gopi
doaj +1 more source
In Situ, 2012 The mills which are to be seen scattered over the old maps of the Cotentin Peninsula bear witness to forgotten customs. They left their mark on local landscapes even after they had been abandoned and the roads leading to them were no longer frequented ...
Benoît Canu
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Paysage, architecture rurale, territoire : de la prise de conscience patrimoniale à la protection
In Situ, 2012 For a long time, heritage protection in France meant the protection of historic monuments, exceptional buildings “of national interest for history or for art”, as the law of 1887 formulated it.
Arlette Auduc
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
LANDSCAPE AND VIDEOART: THE NEW LANDSCAPE OF THE ANTHROPOCENE.
SGEM International Multidisciplinary Scientific Conferences on SOCIAL SCIENCES and ARTS Proceedings, 2019 We live in a new era -the Anthropocene-. And in a new society with its corresponding mentality and consciousness. But, we keep representing and interpreting the landscape, mainly, through the codes inherited from the Romanticism. This research will address artistic proposals that unite videoart and landscape.
openaire +2 more sources
PLoS Biology, 2003 Open-access publication is inarguably valuable to science and to the public, yet skepticism about the long-term sustainability of open-access publications persists (see Nature, October 9, and Science, October 24). While some fear the effects of the open-access model—which shifts revenue streams from subscription fees to publication fees—on scientific ...
Helen Doyle, Andy Gass, Debra Lappin
openaire +4 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source