Results 61 to 70 of about 1,326,395 (314)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Complexity in landscape ecology

open access: yes, 2020
This book examines key concepts and analytical approaches in complexity theory as it applies to landscape ecology, including complex networks, connectivity, criticality, feedback, and self-organisation.
Sadedin, Suzanne   +3 more
core  

Conflicts between indigenous and scientific concepts of landscape management for wildlife conservation: human-chimpanzee politics of coexistence at Bossou, Guinea

open access: yesRevue de Primatologie, 2014
Environmental conservation policies in Africa have their origin in the forced establishment of nature reserves during the colonial era. Even after African countries became independent, top-down operation of these reserves continued primarily due to ...
Gen Yamakoshi, Vincent Leblan
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Landscape Environmental Monitoring [PDF]

open access: yes, 2011
Landscape pattern is of primary interest to landscape ecologists and landscape metrics are used to quantify landscape pattern. Calculation of landscape metrics is commonly conducted on completely mapped areas based on remotely sensed data.
Svensson, Johan   +2 more
core  

Foraging for identity: the relationships between landscape activities and landscape identity after catastrophic landscape change [Elektronisk resurs] [PDF]

open access: yes, 2019
In this article, we deal with landscape activities in relation to changing landscape identity after a major wildfire in Sweden in 2014. The aim was to investigate the relationships between 22 landscape activities (before the fire) and 2 components ...
Butler, Andrew,   +4 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Landscape morphology : a comparative study of landscape aesthetics. [PDF]

open access: yes, 1992
This research is about landscape aesthetics. Aesthetics is not purely Platonic but a result of human communication with nature which relates to landscape experience and, in turn, reflects and guides the way people appreciate, paint and design.
Wu, Jiahua
core  

СREATION OF LANDSCAPE MAP USING OPEN SOURCE SOFTWARE (ON THE EXAMPLE OF THE NATIONAL PARK «SMOLENSKOYE POOZERYE»)

open access: yesInterCarto. InterGIS, 2016
In landscape mapping is no single technique, so each school has its own method of creating maps. However, one of the initial operations, recognized all schools allocation is called the primary matrix – matrix or locations which latched, usually on the ...
T. V. Vatlina, S. P. Evdokimov
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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