Results 71 to 80 of about 682,231 (268)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Une marginalité spatiale comme clé de lecture des territoires

open access: yesTerritoire en Mouvement, 2011
Until the end of the XIX century and the phylloxeric episode, vine was one of the principal resources in Haute-Saône. According to agricultural statistics, since the nineteen seventies this culture has officially disappeared from most of the villages of ...
Sylvain Estager
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

ECONOMIC AND FINANCIAL ASPECTS OF ACTIVITY IN SC "AGRO ANCA" SRL, RO.IORII DE VEDE, COUNTY TELEORMAN (2011-2012) [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2014
The unit was established in 2008, with the object of activity "permanent cultivation of plants" - NACE Code 011 principal activity "Growing of cereals (except rice), leguminous crops and oil seeds plant".
Radu Lucian PÂNZARU   +1 more
doaj  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Shifting shores: Transformative learning with the city

open access: yesJournal of Social Science Education
Highlights: – Post-human methodologies support geographical experimentation in social science education – Walking with a virtual (Deleuze) landscape manifests the materiality of the city – Diverse temporal and spatial rhythms reveal the subject as
William Smolander, Raine Aiava
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Un projet partagé au service des acteurs : la plateforme d’Observatoires photographiques du paysage en Bretagne (POPP-Breizh)

open access: yesProjets de Paysage, 2016
For the most part, Photographic Observatories of the Landscape are confronted with limiting factors when it comes to facilitating the sharing of documents, the sustainability of archiving and the reliability of metadata as well as the capacity to use it.
Laurence Le Dû-Blayo, Caroline Guittet
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Hacer pueblo con el agua. La práctica ritual de la Apantla en Santa Catarina del Monte, Texcoco, México

open access: yesCahiers des Amériques Latines
The aim of this article is to know how the ritual practice of Apantla builds the “pueblo” of Santa Catarina del Monte. I use the sociology of collectives, the anthropology of ritual, and cultural geography to address the processual idea of making a town ...
Patricia Montiel Rogel
doaj   +1 more source

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