Results 81 to 90 of about 3,064,611 (299)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

The Artificial Landscape: Contemporary Architecture, Urbanism, and Landscape architecture in the Netherlands [PDF]

open access: yes, 2002
Dutch designers ore accustomed to working on land that "is not a natural given but exists by virtue of human ingenuity and technology in water management." For the Dutch the idea of "artificial landscope" is not new.
Hohmann, Heidi
core  

Fine-scale monitoring of catkins reveals an association between catkin concentration and plant community characteristics and microclimate

open access: yesScientific Reports
Catkins, as a significant source of plant-caused pollution, disrupts daily human activities and industrial processes. Despite their impact, catkins have not been included in official environmental quality monitoring indicators, leading to a deficiency in
Xiayuan Mi   +6 more
doaj   +1 more source

Integrating Transcriptomic and GC-MS Metabolomic Analysis to Characterize Color and Aroma Formation during Tepal Development in Lycoris longituba

open access: yesPlants, 2019
Lycoris longituba, belonging to the Amaryllidaceae family, is a perennial bulb bearing flowers with diverse colors and fragrance. Selection of cultivars with excellent colored and scented flowers has always been the breeding aim for ornamental plants ...
Yuanzheng Yue   +9 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Aesthetic creation theory and landscape architecture [Elektronisk resurs]

open access: yes, 2016
In recent decades the landscape architectural discourse has tended to eschew ideas of aesthetics while focusing instead on notions of functional and sustainable design.
Vicenzotti, Vera,   +1 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A framework for landscape assessment [PDF]

open access: yes, 1999
The primary aim of the New Zealand Institute of Landscape Architects (NZILA) conference on landscape assessment, held at Lincoln University on 12-14 March 1999, was to identify the key elements of an assessment framework suitable for use in implementing ...
Swaffield, S
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Revitalizing the Srengseng City Forest as a sustainable ecotourism destination through the integrated landscape management approach

open access: yesSustinere: Journal of Environment and Sustainability
Srengseng City Forest in Jakarta has strong potential as an urban ecotourism. However, it faces several challenges, such as limited green infrastructure, insufficient educational facilities, low economic contribution, and inadequate institutional ...
Silia Yuslim   +3 more
doaj   +1 more source

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