Results 191 to 200 of about 188,104 (310)

Landscape evolution in China's key ecological function zones during 1990-2015. [PDF]

Sci Rep
Liu J, Zhong J.
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Editorial: Continental Basin and Orogenic Processes: Tectonic Deformation and Associated Landscape and Environmental Evolution

Frontiers in Earth Science, 2022
Xuhua Shi, Xuhua Shi, Xuhua Shi, Hanlin Chen, Hanlin Chen, Rong Yang, Rong Yang, Huiping Zhang, Xiaoping Yuan   +8 more
doaj   +1 more source

Gullying and landscape evolution: Lavaka in Lac Alaotra, Madagascar shed light on rates of change and non-anthropogenic controls. [PDF]

Sci Adv
Cox R, Phillips EK, Rakotondrazafy AFM.
europepmc   +1 more source

Neogene fluvial landscape evolution in the hyperarid core of the Atacama Desert. [PDF]

Sci Rep, 2018
Ritter B, Stuart FM, Binnie SA, Gerdes A, Wennrich V, Dunai TJ.   +5 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

The last 1100 years of activity of La Fossa caldera, Vulcano Island (Italy): new insights into stratigraphy, chronology, and landscape evolution. [PDF]

Bull Volcanol
Di Traglia F, Pistolesi M, Bonadonna C, Rosi M.   +3 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Outburst floods provide erodability estimates consistent with long-term landscape evolution. [PDF]

Sci Rep, 2018
Garcia-Castellanos D, O'Connor JE.
europepmc   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source