Results 131 to 140 of about 5,508,906 (294)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
A critical examination of the tourism climate index landscape
Theoretical and Applied ClimatologyAbstract Tourism climate indices have become valuable tools for using raw meteorological data in quantifying and classifying the climatic suitability of a destination for tourism, and to determine the seasonality of optimal conditions to maximise the tourist experience. The initial Tourism Climate Index (TCI) was developed and applied
Ariel S. Prinsloo, Jennifer M. Fitchett
openaire +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Azalea Garden, Minnesota Landscape Arboretum Map
, 2005 Map of the Minnesota Landscape Arboretum with Woodland Azalea Garden highlighted. Map is undated but depicts the Oswald Visitor Center, which opened in 2005.University of Minnesota. Minnesota Landscape Arboretum. (2005).
University of Minnesota. Minnesota Landscape Arboretum
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, 1985 This is the 1985 edition of the Index. The Index is written by student editors, and it is the college’s yearbook. It includes an annual record of events at Wooster. This specific Index is divided into different sections including college life, activities,
Editors, Index, Index Editors,
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Effects of landscape pattern change on waterbird diversity in Xianghai Nature Reserve
Open GeosciencesIn order to study the change of landscape pattern and its impact on waterbird diversity in Xianghai Nature Reserve, this article analyzes the changing landscape pattern of the reserve from 2014 to 2017 at the landscape and type level. Pearson correlation
Zhao Yuelan +3 more
doaj +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Environmental Research LettersAmid accelerating urbanization and severe biodiversity loss in global drylands, reconciling urbanization with habitat conservation is crucial for sustainable development.
Siya Li +9 more
doaj +1 more source