Results 51 to 60 of about 4,814,228 (287)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Landscape Biographies explores the long and complex histories of landscapes from personal and social perspectives. As an essential part of human life-worlds, landscapes have the potential to absorb something of people's lives, works, and thoughts.
core +1 more source
Dynamic Analysis of Landuse Landscape Pattern in Mengyin County,Shandong Province
Shuitu baochi yanjiu, 2011 In order to understand the dynamic changes of landscape pattern characteristics,based on the 1987 and 2007 the typical period of two remote sensing images,we used the RegionManager 5.5,Arc GIS and other geographic information systems software in support ...
LI Huan1 +4 more
doaj
Analysis of the effect of landscape component classification on landscape diversity index
Environmental Research CommunicationsAbstract The landscape diversity index (LDI) is an important level in biodiversity conservation, and its scale dependence has an important role in regional landscape planning and biological conservation. The aim of this study is to analyze in depth the effects of spatial scale changes in the classification of different landscape ...
Biao Ma +3 more
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A GIS-Based Study on Optimized Spatial Distribution of Rural Settlements in Mayang County
Shuitu baochi yanjiu, 2010 Optimum Spatial Distribution of Rural Settlements is an important way to solve the current distribution of scattered and inefficient use of rural settlements.In this paper,Mayang county is taken as an example,by means of GIS spatial analysis and ...
TAN Xue-lan +3 more
doaj
Landscape ecological risk assessment of chongming dongtan wetland in shanghai from 1990 to 2020
Environmental Research Communications, 2023 Landscape ecological risk assessment can assess the stability, vulnerability, and anti-interference ability of the ecosystem based on the characteristics, structure, and function of the landscape in order to determine the degree and distribution of ...
Yong Cao +6 more
doaj +1 more source
Constraints on the spectral index for the inflation models in the string landscape [PDF]
Physical Review D, 2007 We conjecture that the inflation models with trans-Planckian excursions in the field space should be in the swampland. We check this conjecture in a few examples and investigate the constraints on the spectral index for the slow-roll inflation model in string landscape where the variation of inflaton during the period of inflation is less than the ...
openaire +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Response of Variation of Runoff and Sediment to Landscape Pattern in Huangfuchuan Basin
Shuitu baochi yanjiu, 2021 In order to study the landscape pattern of Loess Plateau under the background of sediment reduction in the Yellow River,this paper aims to explore the influence of landscape pattern on runoff and sediment.
LIU Beilei +4 more
doaj