Results 41 to 50 of about 5,176,691 (243)
A distance dependent contagion function for vector-based data [PDF]
, 2011 Landscape pattern is of primary interest to landscape ecologists and landscape metrics are used to quantify landscape pattern. Metrics are commonly defined and calculated on raster-based land cover maps.
Habib Ramezani +7 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Perspective on the Refractive-Index Gas Metrology Data Landscape
Journal of Physical and Chemical Reference Data, 2021 The redefinition of the kelvin has increased focus on thermometry techniques that use the newly fixed value of the Boltzmann constant to realize thermodynamic temperature. One such technique that has advanced considerably in recent years is refractive-index gas thermometry.
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Shuitu baochi yanjiu, 2020 In order to explore the spatial distribution differences of traditional village settlements in Guizhou Province, based on five batches of 725 traditional villages in Guizhou Province and 2017 settlement data, the spatial distribution characteristics and ...
YANG Xingyan, ZHAO Cuiwei
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Dynamic Landscape Fragmentation and the Driving Forces on Haitan Island, China
Land, 2022 Island ecosystems have distinct and unique vulnerabilities that place them at risk from threats to their ecology and socioeconomics. Spatially exhibiting the fragmentation process of island landscapes and identifying their driving factors are the ...
Jingwen Ai +4 more
doaj +1 more source
A framework for landscape assessment [PDF]
, 1999 The primary aim of the New Zealand Institute of Landscape Architects (NZILA) conference on landscape assessment, held at Lincoln University on 12-14 March 1999, was to identify the key elements of an assessment framework suitable for use in implementing ...
Swaffield, S
core
, 2021 The landscapes surrounding power stations commissioned by the nationalised electricity industry and the Central Electricity Generating Board (CEGB) offered significant opportunities for landscape architects in post-war Britain, and had a huge impact on ...
Csepely-Knorr, Luca
core