Results 51 to 60 of about 5,176,691 (243)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Landscape pattern evolution of the north of Hangzhou bay coastal area in Shanghai
Since the 1980s in Shanghai,fast economic development,rapid urbanization,population explosion,all of these phenomena are driving radical changes in landscape pattern of coastal area.The landscape pattern evolution at the coastal regions of the north of ...
LIANG Shuai, GAO Jun
doaj
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Analysis on Land-use and Landscape Change of Wuyu’er River Basin in Heilongjiang
In order to explore the change and its causes of land-use landscape pattern characteristics in Wuyu’er River Basin,by using 1995 and 2000 TM images for basic information in the typical watershed Wuyu’er River Basin in Heilongjiang Province,and 3S ...
LIU Hong-yan1, ZHAO Yu-sen1
doaj
Analysis of the effect of landscape component classification on landscape diversity index
Abstract The landscape diversity index (LDI) is an important level in biodiversity conservation, and its scale dependence has an important role in regional landscape planning and biological conservation. The aim of this study is to analyze in depth the effects of spatial scale changes in the classification of different landscape ...
Biao Ma +3 more
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
In order to determine coupling relationship between coal mining driving force and landscape pattern of land use,GIS and RS technology combined with landscape pattern analysis software FRAGSTATS were applied to analyze the change of landscape spatial ...
WU Wen-yi1, LIU Ying2, YANG Xiao-hui3
doaj
Landscape ecological risk assessment of chongming dongtan wetland in shanghai from 1990 to 2020
Landscape ecological risk assessment can assess the stability, vulnerability, and anti-interference ability of the ecosystem based on the characteristics, structure, and function of the landscape in order to determine the degree and distribution of ...
Yong Cao +6 more
doaj +1 more source
Constraints on the spectral index for the inflation models in the string landscape [PDF]
We conjecture that the inflation models with trans-Planckian excursions in the field space should be in the swampland. We check this conjecture in a few examples and investigate the constraints on the spectral index for the slow-roll inflation model in string landscape where the variation of inflaton during the period of inflation is less than the ...
openaire +2 more sources

