Results 61 to 70 of about 177,351 (312)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Frontiers in Ecology and Evolution, 2017 Environmental impact assessment (EIA) before and after the establishment of a Water Conservancy Project (WCP) is of great theoretical and practical importance for assessing the effectiveness of ecological restoration efforts.
Zhi-Xin Zhu +9 more
doaj +1 more source
Ecological Indicators, 2023 The accurate analysis of landscape pattern and ecological process characteristics in rapidly urbanized areas is crucial for formulating policies related to differentiated urban development and landscape management measures.
Changyue Hu +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Index of landscape patterns of various landscapes.
, 2023 Index of landscape patterns of various landscapes.
Qinfei Bai (17357525) +5 more
core +1 more source
Quantifying Landscape Pattern–Hydrological Process Linkage in Northwest Iran
Atmosphere, 2023 The enormous heterogeneity and complexity of landscape patterns and their linkage with the hydrological responses have rarely been quantified and cataloged, especially in ungauged regions.
Ali Rasoulzadeh +5 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Identifying realistic recovery targets and conservation actions for tigers in a human dominated landscape using spatially-explicit densities of wild prey and their determinants [PDF]
, 2014 Aim Setting realistic population targets and identifying actions for site and landscape-level recovery plans are critical for achieving the global target of doubling wild tiger numbers by 2022.
MacMillan, Douglas C. +2 more
core +1 more source
Shuitu Baochi Xuebao[Objective] Chongqing is a mega-metropolis located in the southwestern hilly region. The rising population and extensive economic development have led to rapid urban landscape ascent and expansion, resulting in a dual urban-rural and 3D spatial structure
WEI Mengyu +6 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source