Results 31 to 40 of about 3,138,500 (297)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
4D, 2015 The article starts with a short landscape-painting introduction, and then it will be followed by a case-study demonstrating the role of landscape patterns of a Transylvanian ...
Anna Eplényi
doaj
Ecological Indicators, 2023 The accurate analysis of landscape pattern and ecological process characteristics in rapidly urbanized areas is crucial for formulating policies related to differentiated urban development and landscape management measures.
Changyue Hu +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ecological Indicators, 2022 Landscape management and planning is an important way to mitigate climate change. Previous studies have proved landscape pattern (composition and configuration) was correlated to thermal environment based on a single image data in time, but the static ...
Jiayang Li +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Scientific ReportsRural landscape health assessment, which integrates ecology and culture, is crucial for China’s rural revitalization strategy. However, existing studies primarily focus on large-scale regions, neglecting small-scale areas.
Siqi Sun +6 more
doaj +1 more source
Analysis of the Spatial Pattern and Driving Forces of Linpan in Western Sichuan [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information SciencesThis study aims to explore the landscape pattern and its driving forces of Linpan in western Sichuan, aiming to gain a deeper understanding of the spatial distribution of this unique rural settlement form.
J. Du +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Landscape ecology integrates pattern and process in river corridors
, 1999 Landscape ecology holds the potential for developing a truly holistic perspective of river corridors, one that rigorously integrates structure, dynamics, and function.
Tockner, K. (author) +2 more
core +1 more source