Results 51 to 60 of about 226,550 (307)

Spatio-temporal characteristics of traditional village landscape pattern and its influencing factors from the perspective of tourism development: a case study of Huangcheng Village, China

Journal of Asian Architecture and Building Engineering
Tourism development promotes economic income and cultural protection of traditional villages, but it also disturbs their landscape pattern and ecosystem.
Zurui Lin, Kaiyi Chen, Kai Jiao, Zixuan Li   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Response of Ecosystem Service Value to Landscape Pattern Changes under Low-Carbon Scenario: A Case Study of Fujian Coastal Areas

, 2022
Assessing the influence of landscape pattern changes on ecosystem service value (ESV) is critical for developing land-use polies and increasing ecosystem services.
Shihe Zhang, Guo Cai, Baoyin Li, Fazi Zhang, Yuying Lin, Linsheng Wen   +5 more
core   +1 more source

FracL: A Tool for Characterizing the Fractality of Landscape Gradients from a New Perspective

ISPRS International Journal of Geo-Information, 2019
The past several years have witnessed much progress in landscape ecology and fractal analysis. In landscape ecology, the gradient model of landscape patterns (i.e., landscape gradient) has emerged as a new operating paradigm, where most landscape metrics
Peichao Gao, Samuel A. Cushman, Gang Liu, Sijing Ye, Shi Shen, Changxiu Cheng   +5 more
doaj   +1 more source

Effects of landscape patterns and their changes on ecosystem health under different topographic gradients: A case study of the Miaoling Mountains in southern China

Ecological Indicators, 2023
Ecosystem health is an essential characterization of landscape pattern ecological effects, and refined analysis of the variability of landscape pattern changes on ecosystem health in mountainous areas is of great significance for the synergistic ...
Min Li, Guangjie Luo, Yangbing Li, Ying Qin, Juan Huang, Jingjing Liao   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Using network centrality measures to manage landscape connectivity

, 2008
We use a graph-theoretical landscape modeling approach to investigate how to identify central patches in the landscape as well as how these central patches influence (1) organism movement within the local neighborhood, and (2) the dispersal of organisms ...
Bodin, Orjan, Estrada, Ernesto, Ramon y Cajal program Spain (Funder), , Ramon y Cajal program Spain (Funder), , Swedish Research Council (Funder), Department for Reserch Cooperation, Swedish International Development Cooperation Agency (Funder), Estrada, E., , Swedish Reserach Council for Environment, Agricultural Sciences, Bodin, O., Swedish Reserach Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) (Funder), Swedish Research Council (Funder), , Department for Reserch Cooperation, Swedish International Develo   +11 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effects of landscape pattern change on waterbird diversity in Xianghai Nature Reserve

Open Geosciences
In order to study the change of landscape pattern and its impact on waterbird diversity in Xianghai Nature Reserve, this article analyzes the changing landscape pattern of the reserve from 2014 to 2017 at the landscape and type level. Pearson correlation
Zhao Yuelan, Liu Jiping, Li Huifen, Zhao Dandan   +3 more
doaj   +1 more source