Results 61 to 70 of about 226,550 (307)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
LandWith rapid urbanization, the types of land in China’s cities are continuously evolving, irreversibly impacting the habitat patches within urban areas. However, the development of park cities has reversed this trend to some extent, particularly in Chengdu,
Rong Lin +4 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Pattern and process: the language of landscape ecology
Landscape Review, 1997 Landscape architecture and landscape ecology are fundamentally concerned with the connections between landscape pattern and ecological process. Landscape ecologists typically assume that process creates pattern; landscape architects address pattern with ...
Catherine Alington
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Grain size effect of landscape in Jiangxi Guanshan subtropical evergreen broad-leaved forest
Guangxi ZhiwuDetermining an appropriate grain size is crucial in landscape pattern analysis and ecological research. In order to gain deeper insights into the spatial diversity and dynamic characteristics of landscape pattern, based on the survey data of the 12 hm2 ...
RAN Huan1, LAN Yong2, DAI Yufeng2, XIONG Yong2, WEN Renquan1, SONG Qingni1, YANG Qingpei1, LIU Jun1*
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Patterns and Evolution of Nucleotide Landscapes in Seed Plants [PDF]
The Plant Cell, 2012 Nucleotide landscapes, which are the way base composition is distributed along a genome, strongly vary among species. The underlying causes of these variations have been much debated. Though mutational bias and selection were initially invoked, GC-biased gene conversion (gBGC), a recombination-associated process favoring the G and C over A and T bases,
Serres-Giardi, Laurana +3 more
openaire +4 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 2011 The development of conservation strategies to mitigate the impact of invasive species requires knowledge of the species ecology and distribution. This is, however, often lacking as collecting biological data may be both time-consuming and resource ...
Sonja Preuss +10 more
core +1 more source