Results 61 to 70 of about 3,138,500 (297)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FracL: A Tool for Characterizing the Fractality of Landscape Gradients from a New Perspective
ISPRS International Journal of Geo-Information, 2019 The past several years have witnessed much progress in landscape ecology and fractal analysis. In landscape ecology, the gradient model of landscape patterns (i.e., landscape gradient) has emerged as a new operating paradigm, where most landscape metrics
Peichao Gao +5 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Landscape Biographies explores the long and complex histories of landscapes from personal and social perspectives. As an essential part of human life-worlds, landscapes have the potential to absorb something of people's lives, works, and thoughts.
core +1 more source
Multiple Scale Analysis of Landscape Fragmentation Pattern Scenarios in East Wanda Mountains
Shuitu baochi yanjiu, 2009 According to the real landscape of East Wanda Mountains,PCA was used to analyze the multiple scale landscape fragmentation pattern scenarios.The results showed that: PCA can expressed multiple scale landscape fragmentation process accurately in East ...
GAO Mei-xiang1 +2 more
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Shuitu baochi yanjiu, 2011 In order to determine coupling relationship between coal mining driving force and landscape pattern of land use,GIS and RS technology combined with landscape pattern analysis software FRAGSTATS were applied to analyze the change of landscape spatial ...
WU Wen-yi1, LIU Ying2, YANG Xiao-hui3
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A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Pattern and process: the language of landscape ecology
Landscape Review, 1997 Landscape architecture and landscape ecology are fundamentally concerned with the connections between landscape pattern and ecological process. Landscape ecologists typically assume that process creates pattern; landscape architects address pattern with ...
Catherine Alington
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