Results 81 to 90 of about 998,860 (301)
The surface features and soil pattern of the Hamilton basin [PDF]
, 1967 The Holocene history of the Hamilton basin and development of the soil pattern are closely related. The basin was partly filled by the large alluvial fan of the Waikato River which partly buried a hilly, ash-covered landscape.
McCraw, J.D.
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Optimising the spatial pattern of landscape revegetation [PDF]
The spatial pattern of landscape reconstruction makes a substantial difference to environmental outcomes. We develop a spatially explicit bio-economic model that optimises the reconstruction of a heavily cleared landscape through revegetation.
Pannell, David J. +4 more
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Landscape preferences and patterns of residential development [PDF]
Journal of Urban Economics, 2005 Abstract I analyze a model of residential location choice where people derive utility from their proximity to open space. When people have such landscape preferences then (1), equilibrium residential development is mixed with undeveloped land (2), equilibrium land price gradients depend sensitively on how land markets are organized, are not generally
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Spatial Externalities in Agriculture: Empirical Analysis, Statistical Identification, and Policy Implications [PDF]
Spatial externalities can affect economic welfare and landscape pattern by linking farm returns on adjoining parcels of land. While policy can be informed by research that documents spatial externalities, statistically quantifying the presence of ...
Barham, Bradford L. +2 more
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Defending Korematsu?: Reflections on Civil Liberties in Wartime [PDF]
, 2003 According to Justice William J. Brennan, After each perceived security crisis ended, the United States has remorsefully realized that the abrogation of civil liberties was unnecessary.
Tushnet, Mark V.
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source