Results 81 to 90 of about 3,138,500 (297)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Landscape preferences and patterns of residential development [PDF]

open access: yesJournal of Urban Economics, 2005
Abstract I analyze a model of residential location choice where people derive utility from their proximity to open space. When people have such landscape preferences then (1), equilibrium residential development is mixed with undeveloped land (2), equilibrium land price gradients depend sensitively on how land markets are organized, are not generally
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Grain size effect of landscape in Jiangxi Guanshan subtropical evergreen broad-leaved forest

open access: yesGuangxi Zhiwu
Determining an appropriate grain size is crucial in landscape pattern analysis and ecological research. In order to gain deeper insights into the spatial diversity and dynamic characteristics of landscape pattern, based on the survey data of the 12 hm2 ...
RAN Huan1, LAN Yong2, DAI Yufeng2, XIONG Yong2, WEN Renquan1, SONG Qingni1, YANG Qingpei1, LIU Jun1*
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evaluation of the Impact of Urbanization and Ecological Civilization Construction on Landscape Ecological Risk in Huaxi District of Guiyang Characterized as Karst Mountain City

open access: yesShuitu baochi yanjiu, 2023
[Objective] The aim of this study is to explore the dynamic changes of landscape pattern and landscape ecological risk in Huaxi District, Guiyang City, a karst mountain city, and provide a basis for the protection and improvement of ecological ...
CHENG Yuzhuo   +4 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Texas Pattern Jury Charges [PDF]

open access: yes, 2011
Guide listing pattern jury charges to assist the bench and bar in preparing the court's charge for the jury in the state of Texas, including general instructions for the guilt/innocence and punishment stages of the trial, and instructions related to ...
State Bar of Texas. Committee on Pattern Jury Charges.   +1 more
core  

Analysis on Landscape Spatial Patterns of Different Topography on County Scale——A Case Study of Liling City,Hu’nan Province

open access: yesShuitu baochi yanjiu, 2009
Topography is one of the most important natural factors influencing the landscape spatial pattern.To analyze the relationship between topography types and landscape spatial pattern,a case study was carried out in Liling city,Hu’nan province,which was ...
LIU Yan-yan1   +4 more
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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