Results 91 to 100 of about 3,138,500 (297)

Textile Transfer Pattern

open access: yes, 1934
Envelope for a McCall Kaumagraph Transfer pattern to make appliqué tulip flower and flower pot designs for suggested items such as kitchen curtains, table runners and pot holders; includes illustrations of finished pieces and instructions for ...
McCall Pattern Company
core  

Spatiotemporal analysis of Indian megacities [PDF]

open access: yes, 2008
Urbanization is arguably the most dramatic form of highly irreversible land transformation. While urbanization is a worldwide phenomenon, it is exceptionally dynamic in India, where unprecedented urban growth rates have occurred over the last 30 years ...
Taubenböck, Hannes   +5 more
core  

Using landscape history to predict biodiversity patterns in fragmented landscapes

open access: yesEcology Letters, 2013
AbstractLandscape ecology plays a vital role in understanding the impacts of land‐use change on biodiversity, but it is not a predictive discipline, lacking theoretical models that quantitatively predict biodiversity patterns from first principles. Here, we draw heavily on ideas from phylogenetics to fill this gap, basing our approach on the insight ...
Ewers, R.M.   +7 more
openaire   +4 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Science for action at the local landscape scale

open access: yes, 2013
For landscape ecology to produce knowledge relevant to society, it must include considerations of human culture and behavior, extending beyond the natural sciences to synthesize with many other disciplines.
Liu, Jianguo   +28 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Change of Landscape Pattern of Small Watershed in Mountain Area

open access: yesShuitu baochi yanjiu, 2007
Landscape pattern and its ecological effect is the research focus of landscape ecology.So the authors take Jinyunchuan watershed as an example,analyzing the change of landscape pattern in 1996~2006.The study result shows that: all the kinds of patches ...
ZHANG Ming-liang, WANG Hai-xia
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Carefree Pattern

open access: yes, 1975
McCall's Carefree Pattern #4387 by Halston to make stretch knit cape with asymmetrical drape and flared skirt with waistband, including illustrations of the finished pieces and information about sizing and construction on the ...
Halston, 1932-1990   +1 more
core  

Home - About - Disclaimer - Privacy