Results 111 to 120 of about 226,550 (307)

Human–Nature Interaction Pattern Design in Landscape Architecture

Landscape architecture has long engaged esthetics, ecological process, and cultural meaning, and contemporary practice increasingly embraces systemic and process-based approaches.
Hongfei Li, Peter H. Kahn
core   +1 more source

Impacts of spatio-temporal change of landscape patterns on habitat quality across Zayanderud Dam watershed in central Iran

Scientific Reports
The biodiversity of an ecosystem is greatly influenced by the spatio-temporal pattern of the landscape. Understanding how landscape type affects habitat quality (HQ) is important for maintaining environmental and ecological sustainability, preserving ...
Seyed Mohammad-reza Abolmaali, Mostafa Tarkesh, Seyed Alireza Mousavi, Hamidreza Karimzadeh, Saeid Pourmanafi, Sima Fakheran   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimising the spatial pattern of landscape revegetation

The spatial pattern of landscape reconstruction makes a substantial difference to environmental outcomes. We develop a spatially explicit bio-economic model that optimises the reconstruction of a heavily cleared landscape through revegetation.
Pannell, David J., Roberts, Anna M., Polyakov, Maksym, Park, Geoff, Rowles, Alexei   +4 more
core  

A landscape pattern gradient analysis method coupling wavelet algorithm for balancing development and protection activities of the coastal zone: A case study

Ecological Indicators
Due to the economic importance and ecological vulnerability of coastal areas, the optimization of spatial patterns is important for the sustainable development of coastal zones.
Xingpo Liu, Zixuan Yang, Yaozhi Chai
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

The landscape ecology of butterflies in traditionally managed Norwegian farmland [PDF]

, 1998
The modernisation of agriculture has lead to changes in Norwegian farming landscapes that have consequences for butterfly distribution and abundance.
Fjellstad, W.J., Fjellstad, Wendy Jane
core  

Analysis of Landscape Pattern Evolution and Impact Factors in the Mainstream Basin of the Tarim River from 1980 to 2020

Hydrology
The mainstream basin of the Tarim River serves as a vital ecological security barrier that prevents the merging and expansion of deserts and an important strategic corridor directly linking Qinghai and Xinjiang.
Lili Jiang, Yating Li
doaj   +1 more source

Variation trend prediction of ground-level ozone concentrations with high-resolution using landscape pattern data. [PDF]

PLoS One, 2023
Mei Y, Xiang X, Wang Z, Xiang D.
europepmc   +1 more source