Results 131 to 140 of about 998,860 (301)

Agriculture and Sustainability: a GIS Based Model to Appraise Incentive Policy [PDF]

open access: yes, 2015
Agriculture is the major form of protection of local identities and sustainability and one of the most fragile Italian economic sectors, exposed to fluctuations of the financial/economic crisis.
Gagliano, F., Giuffrida, S., Napoli, G.
core  

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Plant functional constraints on foliar N:P ratios in a tropical forest landscape [PDF]

open access: yes, 2009
Although large scale analyses of foliar N:P ratios suggest and overall pattern of P limitation in tropical forests, analyses within the biome are less indicative of a consistent pattern of nutrient limitation.
Carlos A. Sierra
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Iceland as a Landscape Investigation Pattern

open access: yesNordicum-Mediterraneum, 2007
Nowadays Icelanders continue an ancient dialogue. Nature is part of their soul and they take with them bits of their terrestrial landscape when they move to the elsewhere.
Campanini, Manuela Silvia
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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