Results 141 to 150 of about 226,550 (307)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Monitoring the Landscape Pattern and Characteristics of Non-Point Source Pollution in a Mountainous River Basin. [PDF]

Int J Environ Res Public Health, 2021
Liu Y, Yang C, Yu X, Wang M, Qi W.
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Landscape Pattern Evolution Processes of Wetlands and Their Driving Factors in the Xiong'an New Area of China. [PDF]

Int J Environ Res Public Health, 2021
Yang M, Gong J, Zhao Y, Wang H, Zhao C, Yang Q, Yin Y, Wang Y, Tian B.   +8 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The study on landscape pattern change of wetland based on GIS and RS: An example of Dongting Lake area

, 2008
As one of three important ecosystems in the world ,wetland has complex , various and specific functions. With the change of its component ,the wetland ecosystem function is changing .
Liang,Shou-Zhen, Shou-zhen Liang
core   +1 more source

Study on the Water Quality Characteristics of the Baoan Lake Basin in China under Different Land Use and Landscape Pattern Distributions. [PDF]

Int J Environ Res Public Health, 2022
Ren W, Wu X, Ge X, Lin G, Feng L, Ma W, Xu D.   +6 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

4.7. Landscape Pattern

, 2007
The landscape-level spatial pattern of forest cover gives information on the size, shape and spatial distribution of forests in a landscape as it refl ects the potential of landscape to provide forest habitats.
KOSKELA J, PARVIAINEN J, BOZZANO M, ESTREGUIL Christine   +3 more
core  

Using urban landscape pattern to understand and evaluate infectious disease risk. [PDF]

Urban For Urban Green, 2021
Ye Y, Qiu H.
europepmc   +1 more source