Results 101 to 110 of about 3,138,500 (297)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Applying Landscape Ecological Metrics on Land Use Change in Lanyang Plain [PDF]
Land use is the human activity affecting by economical, cultural, political and historical factors and presents complex, uncertainty and spatiotemporal characteristics.
Hsiao-Wen Wang
core
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
, 1973 McCall's Carefree Pattern #3818 by Halston to make a jacket with short notched lapels, shirt with convertible collar and center front button closure, and flared pants, including illustrations of the finished pieces and information about sizing and ...
Halston, 1932-1990 +1 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Landscape pattern and process of modern oasis in Xinjiang, China
, 2007 Based on Landsat MSS/TM images and CBERS-02 CCD data of Beitun Oasis in Ertix River Watershed in the years of 1972, 1989, 1999 and 2005, the landscape patterns for the past 30 years were analyzed. Using the GIS data collective platform, we calculated the
Huang +14 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Shuitu baochi yanjiu, 2014 Our purpose was to quantitatively analyze land use landscape pattern and divide land use landscape into several types in Sheyang.We combined GIS,gradient analysis and landscape analysis method to calculate landscape pattern indices based on the national ...
ZHU Bin, ZHANG Xiao-lin
doaj
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source