Results 131 to 140 of about 437,940 (300)
Open GeosciencesCoastal zones have intense human activity and are ecologically fragile. Assessing ecological risks in coastal zones is crucial to promoting ecological safety and sustainable development for coastal cities.
Han Ying +3 more
doaj +1 more source
Ecological IndicatorsAs a key ecological barrier in China, the evolution of ecosystem service value (ESV) on the karst plateau is crucial for regional sustainable development. Using multitemporal remote sensing data from 2005 to 2020, the impacts of landscape pattern changes
Jiaying Tan +4 more
doaj +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Landscape-scale establishment and population spread of yellow-cedar (Callitropsis nootkatensis) at a leading northern range edge [PDF]
, 2016 Thesis (M.S.) University of Alaska Fairbanks, 2016Yellow-cedar is a long-lived conifer of the North Pacific Coastal Temperate Rainforest region that is thought to be undergoing a continued natural range expansion in southeast Alaska.
Krapek, John P.
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Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Umbrella species as a conservation planning tool [PDF]
, 2006 In northern Europe, a long history of anthropogenic land use has led to profound changes within forest ecosystems. One of the proposed approaches for conservation and restoration of forest biodiversity is the use of umbrella species, whose conservation ...
Roberge, Jean-Michel
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Impact of landscape pattern on habitat quality in the Yangtze River Economic Belt from 2000 to 2030
Ecological IndicatorsRecently, rapid economic development of the Yangtze River Economic Belt region in China and the growing problem of regional habitat quality have seriously threatened the process of biodiversity conservation in the Yangtze River Basin. Studying the impact
Fei Yang +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
A Fifty-Year Sustainability Assessment of Italian Agro-Forest Districts [PDF]
, 2016 DistrictAs cropland management and land use shifted towards more intensive practices, global land degradation increased drastically. Understanding relationships between ecological and socioeconomic drivers of soil and landscape degradation within these
Clemente, Matteo +4 more
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