Results 131 to 140 of about 74,383 (294)
Open GeosciencesCoastal zones have intense human activity and are ecologically fragile. Assessing ecological risks in coastal zones is crucial to promoting ecological safety and sustainable development for coastal cities.
Han Ying +3 more
doaj +1 more source
Ecological IndicatorsAs a key ecological barrier in China, the evolution of ecosystem service value (ESV) on the karst plateau is crucial for regional sustainable development. Using multitemporal remote sensing data from 2005 to 2020, the impacts of landscape pattern changes
Jiaying Tan +4 more
doaj +1 more source
The industrial landscape constitutes a crucial aspect of a region’s historical and cultural identity, serving as a valuable asset in the development of industrial tourism.
Qingmiao Li, Yan Song, Mi Yan
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Spatial Impact of Rural Landscape Pattern on Ecosystem Service in Hangzhou
ObjectiveChanges in landscape pattern often bring about alterations in the structure, process, and function of ecosystem. In the context of rapid urbanization, drastic changes in land use/land cover (LULC) significantly disturb the structure and function
Yiren XU +3 more
core +1 more source
Spatio-temporal cross-city comparison using multisensoral remote sensing for Mexican cities
, 2011 Our planet is more and more transforming into an urban world, in which the dynamics of urbanization have overcome the ability to govern cities. In a situation of uncoordinated urban growth, regional and urban planning lack technologies and methodologies ...
Taubenböck, Hannes +9 more
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Impact of landscape pattern on habitat quality in the Yangtze River Economic Belt from 2000 to 2030
Ecological IndicatorsRecently, rapid economic development of the Yangtze River Economic Belt region in China and the growing problem of regional habitat quality have seriously threatened the process of biodiversity conservation in the Yangtze River Basin. Studying the impact
Fei Yang +3 more
doaj +1 more source