Results 111 to 120 of about 74,383 (294)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stage-Dependent Evolution of Floodplain Landscapes in the Lower Yellow River Under Dam Regulation

open access: yesLand
The floodplain landscape of the lower Yellow River is jointly shaped by natural water-sediment processes and human activities. With intensified regulation by large reservoirs and increasing human development intensity, the landscape pattern of the ...
Xiaohong Wei   +3 more
doaj   +1 more source

The landscape ecology of butterflies in traditionally managed Norwegian farmland [PDF]

open access: yes, 1998
The modernisation of agriculture has lead to changes in Norwegian farming landscapes that have consequences for butterfly distribution and abundance.
Fjellstad, W.J., Fjellstad, Wendy Jane
core  

Characterizing forest fragmentation : Distinguishing change in composition from configuration

open access: yes, 2014
This project was funded by the Government of Canada through the Mountain Pine Beetle Program, a three-year, $100 million program administered by Natural Resources Canada, Canadian Forest Service. Additional information on the Mountain Pine Beetle Program
Wulder, M.A., Long, J.A., Nelson, T.A.
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Landscape pattern dynamic change analysis based on eco-hydrological process in the lower reaches of Tarim River, China

open access: yes, 2008
Landscape pattern and eco-hydrological process had changed greatly after seven times emergency water transportation in the lower reaches of Tarim River, Xinjiang, China.
Qing, Huang1, 2   +4 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The impacts of urban landscape pattern on urban land surface temperature - taking Urumqi as an example

open access: yes, 2009
Urbanization has become an important contributor for global warming and urban air temperature is rising gradually in all the cities. It means that urban land use and land cover (LULC) changed became critical in determining the urban environment quality ...
Bao   +8 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Landscape Pattern Evolution and Optimization Strategy in Wuhan Urban Development Zone, China

open access: yes, 2018
With the rapid development of urbanization process in China, its environmental protection pressure is severely tested. So, analyzing and optimizing the landscape pattern is an important measure to ease the pressure on the ecological environment.
Fei Dai, Feng Yue
core   +1 more source

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