Results 31 to 40 of about 946,909 (302)

Pedestrian Dynamic Thermal Comfort Analysis to Optimize Using Trees in Various Urban Morphologies: A Case Study of Cairo City

open access: yesLand
Considering the impacts of climate change on the goal of obtaining sustainable and healthier cities, this research aimed to analyze and assess the impact of different urban forms with different trees densities on the dynamic physiological equivalent ...
Ahmed Yasser Abdelmejeed   +1 more
doaj   +1 more source

What the ‘green city’ is up to: Two lenses of criticism for the green facades of Oluf Bager Plaza in Odense, Denmark

open access: yesSpool, 2018
Increasingly celebrated, often without questioning, “green architecture” calls for a substantiated discussion. This article explores how design critique can contribute to the thinking and practice around green architecture, particularly green facades ...
Ann-Charlott Eriksen, Svava Riesto
doaj   +1 more source

Rising Coastal Groundwater as a Result of Sea‐Level Rise Will Influence Contaminated Coastal Sites and Underground Infrastructure

open access: yesEarth's Future, 2023
Sea‐level rise (SLR) will cause coastal groundwater to rise in many coastal urban environments. Inundation of contaminated soils by groundwater rise (GWR) will alter the physical, biological, and geochemical conditions that influence the fate and ...
K. Hill   +4 more
doaj   +1 more source

From Landscape Atlas to Flemish Heritage Landscapes: using landscape inventories to formulate landscape quality objectives in a participative process [PDF]

open access: yes, 2011
The European Landscape Convention recommends the realisation of landscape policy, meaning “an expression by the competent public authorities of general principles, strategies and guidelines that permit the taking of specific measures aimed at the ...
Antrop, Marc, Van Eetvelde, Veerle
core   +1 more source

Evaluation of buffer-radius modelling approaches used in forest conservation and planning [PDF]

open access: yes, 2010
Spatial modelling approaches are increasingly being used to direct forest management and conservation planning at the landscape scale. A popular approach is the use of buffer-radius methods, which create buffers around distinct forest habitat patches to ...
Bailey, S.   +3 more
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Territorial Cohesion in the Context of Interregional and Transnational Cooperation [PDF]

open access: yes, 2010
This paper draws on experience from the Interreg IIIC project ProgreSDEC, covering local and regional authorities from Greece, Italy, and Spain cooperating with each other in interregional and transnational projects.
Stein, Axel
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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