Results 31 to 40 of about 872,744 (314)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Cold Protection of Landscape Plants
EDIS, 2014 This document discusses the impact of cold temperatures on landscape plants in Florida, highlighting the differences between radiational and advective freezes. It explains how tropical, subtropical, and temperate plants respond to cold, and provides strategies for protecting plants before, during, and after a freeze.
Sydney Park Brown +2 more
openaire +3 more sources
La convention européenne des paysages: quels enseignements pour le Québec?
VertigO, 2015 Nowadays, landscape is an important resource for rural areas. But, this recognition is not forthcoming in Quebec. First, to understand this fact and propose some actions to help close this gap, the article focuses on the European Landscape Convention ...
Gérald Domon, Julie Ruiz
doaj +1 more source
Mountain Cryosphere Landscapes in South America: Value and Protection
Conservation, 2023 Mountain landscapes support hydric and biodiversity potential under different ownership and land use perspectives. A focal point justifying their preservation is often the legislation’s ethical endorsement. Yet, when scales for assessment diverge without
Sebastián Ruiz-Pereira +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
From Landscape Atlas to Flemish Heritage Landscapes: using landscape inventories to formulate landscape quality objectives in a participative process [PDF]
, 2011 The European Landscape Convention recommends the realisation of landscape policy, meaning “an expression by the competent public authorities of general principles, strategies and guidelines that permit the taking of specific measures aimed at the ...
Antrop, Marc, Van Eetvelde, Veerle
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Barometr Regionalny, 2015 Landscape protection and planning have attracted the attention of experts in many branches of science and industry. The growing interest in landscape management reflects concerns over environmental degradation that deteriorates the quality of life ...
Adam Senetra +2 more
doaj +1 more source