Results 51 to 60 of about 872,744 (314)
Landscape and tourism potential in the protected landscape areas [PDF]
Reasons to travel and to visit concrete destinations in the Czech Republic are especially the nature and cultural/historical sightseeing. The presented paper specializes on the first reason and it studies the specific landscape features together with the primary tourism potentials.
Jana MIKULEC, Michaela ANTOUŠKOVÁ
openaire +2 more sources
Is TRIPS suffering from Big Giant’s Syndrome: Good Economics versus Self Interest? [PDF]
The paper discusses TRIPS as a protection measure on knowledge and new technologies through property rights and analyses the Southern concern if protection of new technologies by means of TRIPS may mean that South can no longer imitate the North in ...
Dawood, Mamoon
core
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Heritage Protection Versus Individual Interests in a Post-Socialist Country: the Case of Mšeno, Czech Republic [PDF]
Large-scale investment is routinely believed to be the main danger to urban heritage. The measures designed to sustain heritage thus traditionally focus on steering investment into respectful ways of real-estate development.
Nowotny, Vojta +2 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Following the increase in protected territories over recent years, emphasis has been laid on improving nature conservation and management effectiveness. In particular, special attention has been given to areas where the interaction between people and the
Antonio Leone +3 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
LANDSCAPE PROTECTION IN GAS PRODUCTION
Due to the growing gas production in the country and the growing demand for oil products, one of the challenges we face is the comprehensive and rational use of our mineral resources and their preservation and protection.
Togayev A.I +2 more
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ecosystem disservices (EDS)—ecosystem properties and functions that cause discomfort or harm—often shape public attitudes to urban biodiversity more strongly than ecosystem services, yet they remain weakly integrated into inclusive spatial planning. This
Anton Shkaruba +3 more
doaj +1 more source

