Results 101 to 110 of about 1,983,901 (377)

Evolutionary Dynamics and Optimization: Neutral Networks as Model-Landscapes for RNA Secondary-Structure Folding-Landscapes

open access: yes, 1995
We view the folding of RNA-sequences as a map that assigns a pattern of base pairings to each sequence, known as secondary structure. These preimages can be constructed as random graphs (i.e. the neutral networks associated to the structure $s$).
Christian Reidys   +3 more
core   +3 more sources

The Book as a landscape [PDF]

open access: yes, 2011
There is a long tradition of regarding landscapes as texts and texts as landscapes. Characterizing visually experienced nature as a text implies stressing its meaningfulness, its character as a message or an expression.
Schmitz-Emans, Monika
core  

Control landscapes for a class of non-linear dynamical systems: sufficient conditions for the absence of traps

open access: yes, 2017
We establish three tractable, jointly sufficient conditions for the control landscapes of non-linear control systems to be trap free comparable to those now well known in quantum control.
Rabitz, Herschel   +2 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Rewilding soil and litter invertebrates and fungi increases decomposition rates and alters detritivore communities

open access: yesEcology and Evolution
Habitat degradation and associated reductions in ecosystem functions can be reversed by reintroducing or ‘rewilding’ keystone species. Rewilding projects have historically targeted restoration of processes such as grazing regimes or top‐down predation ...
Peter Contos   +6 more
doaj   +1 more source

Cover-Encodings of Fitness Landscapes

open access: yes, 2018
The traditional way of tackling discrete optimization problems is by using local search on suitably defined cost or fitness landscapes. Such approaches are however limited by the slowing down that occurs when the local minima that are a feature of the ...
Klemm, Konstantin   +2 more
core   +1 more source

Exploring constrained quantum control landscapes [PDF]

open access: yes, 2012
The broad success of optimally controlling quantum systems with external fields has been attributed to the favorable topology of the underlying control landscape, where the landscape is the physical observable as a function of the controls.
Guckenheimer J.   +3 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Winds of Change: Urgent Challenges and Emerging Opportunities in Submerged Prehistory, a Perspective from the North Sea

open access: yesHeritage
Development of the continental shelf has accelerated significantly as nations around the world seek to harness offshore renewable energy. Many areas marked for development align with submerged palaeolandscapes. Poorly understood and difficult to protect,
Vincent Gaffney   +5 more
doaj   +1 more source

Inhabiting - landscapes and natures [PDF]

open access: yes, 2002
About the book: The Handbook of Cultural Geography presents a state of the art assessment of the key questions informing cultural geography. Emphasizing the intellectual diversity of the discipline, the Handbook presents a comprehensive statement of the ...
Hinchliffe, Steve
core  

Home - About - Disclaimer - Privacy