Results 101 to 110 of about 432,625 (307)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Pesticide‐Free Rice Paddies Promote Diverse and Distinct Aquatic Invertebrate Communities in Cool‐Temperate Agroecosystems

open access: yesEcology and Evolution
Freshwater wetlands are rapidly declining due to the expansion of agriculture and urbanisation, resulting in significant biodiversity loss. In the Swiss lowlands, 90% of wetlands have been lost. Researchers and farmers are therefore jointly exploring the
Thea Bulas   +4 more
doaj   +1 more source

[Imaginary Landscapes Student Demos 34]

open access: yes, 2003
Wet on wet landscape in black, blue, brown and yellow. On same sheet as [Imaginary Landscapes Student Demos 35]Tiff file: 3360x2340 pixels, 22.5 Mb; Display: jpeg, 557x800 pixels ...
Father Edward Catich
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

[Finished Imaginary Landscapes 10]

open access: yes, 2003
Landscape of 2 figures skating on a creek with dark blue sky. Matted with [Finished Imaginary Landscapes 26]Tiff file: 2010x1370 pixels, 7.88 Mb; Display: jpeg, 457x670 pixels ...
Catich, Father Edward Catich
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

[Imaginary Landscapes Student Demos 46]

open access: yes, 2003
Wet on wet landscape in black, dark blue and tan. On same sheet as [Imaginary Landscapes Student Demos 45]Tiff file: 3340x2580 pixels, 24.7 Mb; Display: jpeg, 452x800 pixels ...
Father Edward Catich
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

[Imaginary Landscapes Student Demos 36]

open access: yes, 2003
Wet on wet landscape in black, brown, green, pink and yellow. On same sheet as [Imaginary Landscapes Student Demos 37]Tiff file: 3320x2450 pixels, 23.3 Mb; Display: jpeg, 590x800 pixels ...
Father Edward Catich
core  

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