Results 111 to 120 of about 2,063,143 (381)

Communities of practice in landscapes of practice

open access: yesManagement Learning, 2019
The original formulation of communities of practice primarily focused on describing how learning, meaning, and identity within a community can translate into a sustained practice. Wenger-Trayner et al.
Igor Pyrko, Viktor Dörfler, C. Eden
semanticscholar   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Inhabiting - landscapes and natures [PDF]

open access: yes, 2002
About the book: The Handbook of Cultural Geography presents a state of the art assessment of the key questions informing cultural geography. Emphasizing the intellectual diversity of the discipline, the Handbook presents a comprehensive statement of the ...
Hinchliffe, Steve
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Analyzing Cultural Markers to Characterize Regional Identity for Rural Planning

open access: yesRural Landscapes: Society Environment History, 2018
Regional identity is the shared sense of regional ‘one-ness’, distinctiveness and difference. However, it is an undervalued factor to promote development in lagging rural areas and little is known about methods to reveal its content.
Falco Knaps, Sylvia Herrmann
doaj   +1 more source

Wild bees as winners and losers: Relative impacts of landscape composition, quality, and climate

open access: green, 2021
Melanie Kammerer   +4 more
openalex   +2 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Quark and Lepton Masses from Gaussian Landscapes [PDF]

open access: yes, 2008
The flavor structure of the standard model (SM) might arise from random selection on a landscape. We propose a class of simple models, “Gaussian landscapes,” where Yukawa couplings derive from overlap integrals of Gaussian wave functions on extra ...
Hall, Lawrence J.   +2 more
core  

Complex-network analysis of combinatorial spaces: The NK landscape case

open access: yes, 2012
We propose a network characterization of combinatorial fitness landscapes by adapting the notion of inherent networks proposed for energy surfaces. We use the well-known family of NK landscapes as an example. In our case the inherent network is the graph
Gabriela Ochoa   +4 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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