Results 131 to 140 of about 2,063,143 (381)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Ecosphere, 2019 Landscape patterns created by the structure and form of foundational species shape ecological processes of community assembly and trophic interactions. In recent years, major shifts in foundation species have occurred in multiple ecosystems. In temperate
Jennifer A. Dijkstra +4 more
doaj +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Environmental Research CommunicationsLandscapes of lakes have a significant impact on people’s perceptions of Cultural Ecosystem Services (CES), as well as on their overall sense of well-being.
Jie Wang +6 more
doaj +1 more source
Effective Fitness Landscapes for Evolutionary Systems
, 1999 In evolution theory the concept of a fitness landscape has played an important role, evolution itself being portrayed as a hill-climbing process on a rugged landscape.
Stephens, C. R.
core +2 more sources
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Future information environments: deserts, jungles or parks? [PDF]
, 2006 This paper discusses the basic functions of a common information environment and how they are supported by metadata. Several distinct categories of information landscapes are described, characterised by the availability and quality of metadata at the ...
Dunsire, Gordon
core +1 more source
Addressing Wildfire Risk in a Landscape-Level Scheduling Model: An Application in Portugal [PDF]
, 2014 Liliana Ferreira +3 more
openalex +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source